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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
4.55
Human Site:
S709
Identified Species:
9.09
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
S709
H
W
A
L
F
G
A
S
E
R
G
F
D
P
K
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
G318
I
V
D
V
E
D
L
G
K
I
M
D
H
V
K
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
N726
H
W
A
L
F
G
A
N
E
R
G
F
D
P
K
Dog
Lupus familis
XP_536836
714
81505
S691
H
W
A
L
F
G
A
S
E
R
G
F
D
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
R698
Q
W
A
L
F
G
A
R
E
R
G
F
D
P
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
N718
H
W
A
L
F
G
S
N
Q
L
G
F
D
P
L
Frog
Xenopus laevis
Q2KHP8
735
84095
R712
E
W
A
L
F
G
S
R
E
R
G
F
D
P
L
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
G707
S
W
A
V
F
G
A
G
E
R
G
F
D
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
K690
P
W
A
V
Y
G
S
K
E
Q
G
F
D
P
E
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
V570
A
A
T
P
S
W
A
V
Y
G
A
D
E
G
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
F625
Y
G
A
Q
E
G
G
F
D
P
G
Q
L
R
Y
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
N780
N
G
G
F
A
P
G
N
T
R
V
Y
R
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
6.6
93.3
100
N.A.
86.6
N.A.
N.A.
N.A.
66.6
73.3
73.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
20
100
100
N.A.
86.6
N.A.
N.A.
N.A.
86.6
80
80
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
75
0
9
0
50
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
9
0
0
17
67
0
9
% D
% Glu:
9
0
0
0
17
0
0
0
59
0
0
0
9
0
9
% E
% Phe:
0
0
0
9
59
0
0
9
0
0
0
67
0
0
0
% F
% Gly:
0
17
9
0
0
75
17
17
0
9
75
0
0
9
9
% G
% His:
34
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
9
0
0
0
0
9
42
% K
% Leu:
0
0
0
50
0
0
9
0
0
9
0
0
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
9
0
9
0
0
0
9
0
0
0
67
0
% P
% Gln:
9
0
0
9
0
0
0
0
9
9
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
0
59
0
0
9
9
0
% R
% Ser:
9
0
0
0
9
0
25
17
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
9
% T
% Val:
0
9
0
25
0
0
0
9
0
0
9
0
0
9
0
% V
% Trp:
0
67
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
0
9
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _