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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1
All Species:
16.36
Human Site:
Y116
Identified Species:
32.73
UniProt:
Q9NV66
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV66
NP_060734.2
732
83702
Y116
A
I
I
N
L
K
E
Y
D
P
D
D
H
L
I
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
Y133
A
I
I
N
L
K
E
Y
D
P
D
D
H
L
I
Dog
Lupus familis
XP_536836
714
81505
Y121
A
V
I
N
L
K
E
Y
D
P
D
D
Q
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
G116
D
P
D
D
S
L
I
G
E
I
T
S
K
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
Y125
E
V
I
S
M
G
D
Y
D
P
D
D
C
L
A
Frog
Xenopus laevis
Q2KHP8
735
84095
Y120
E
L
I
N
M
K
E
Y
D
P
D
D
N
L
V
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
F116
E
V
I
D
M
K
D
F
D
P
E
D
R
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
F119
D
V
I
D
L
K
E
F
D
P
E
K
H
V
L
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
L47
E
D
L
F
K
E
K
L
V
I
I
I
A
S
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
I101
K
E
T
L
V
L
F
I
A
S
T
W
D
G
G
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
N126
S
K
K
N
I
G
D
N
E
N
T
A
T
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
91.1
85.7
N.A.
80.5
N.A.
N.A.
N.A.
71.5
71.8
69.8
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
46
93.5
90.8
N.A.
88.1
N.A.
N.A.
N.A.
82.5
83.1
81.8
N.A.
N.A.
N.A.
N.A.
70.4
P-Site Identity:
100
0
100
80
N.A.
0
N.A.
N.A.
N.A.
46.6
66.6
40
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
0
100
93.3
N.A.
20
N.A.
N.A.
N.A.
73.3
93.3
80
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
43.8
N.A.
N.A.
46.7
34
N.A.
Protein Similarity:
58.8
N.A.
N.A.
63.1
50
N.A.
P-Site Identity:
0
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
9
0
0
9
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
17
9
9
25
0
0
25
0
59
0
42
50
9
0
0
% D
% Glu:
34
9
0
0
0
9
42
0
17
0
17
0
0
9
0
% E
% Phe:
0
0
0
9
0
0
9
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
17
0
9
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% H
% Ile:
0
17
59
0
9
0
9
9
0
17
9
9
0
0
17
% I
% Lys:
9
9
9
0
9
50
9
0
0
0
0
9
9
0
0
% K
% Leu:
0
9
9
9
34
17
0
9
0
0
0
0
0
50
9
% L
% Met:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
42
0
0
0
9
0
9
0
0
9
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
59
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
9
0
0
9
9
0
0
0
0
9
0
9
0
9
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
25
0
9
9
9
% T
% Val:
0
34
0
0
9
0
0
0
9
0
0
0
0
9
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _