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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOC1 All Species: 35.45
Human Site: S297 Identified Species: 60
UniProt: Q9NV70 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV70 NP_001020095.1 894 101982 S297 L Q E G D L A S S R G I E A C
Chimpanzee Pan troglodytes XP_001142521 886 101061 S304 L Q E G D L A S S R G I E A C
Rhesus Macaque Macaca mulatta XP_001087347 894 101935 S297 L Q E G D L A S S R G I E A C
Dog Lupus familis XP_532380 894 102004 S297 L Q E G D L A S S R G I E A C
Cat Felis silvestris
Mouse Mus musculus Q8R3S6 894 101859 S297 L Q E G D L V S S R G I E A C
Rat Rattus norvegicus NP_001019941 681 76652 S148 V P S G E N Q S V A G G D E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506171 894 101975 S297 L Q E G D L A S S R G I E A C
Chicken Gallus gallus XP_001232097 895 102211 S297 L Q E G D L T S S R G I E A C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_955891 892 101963 S297 L Q E G D L S S P K G I E A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVG4 889 102677 T314 L D E P D L K T A N G R K A A
Honey Bee Apis mellifera XP_396967 859 98113 Q287 L D I S S T H Q H I L S E A E
Nematode Worm Caenorhab. elegans Q20678 848 97279 F278 L N E E I V S F V N S L Q A V
Sea Urchin Strong. purpuratus XP_787291 869 100242 Q288 L D M P H Q Q Q L A L L D R D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SX85 887 100046 A326 L R V P S E Y A A S L T G G S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 99.5 98.5 N.A. 97.1 70.9 N.A. 95 94 N.A. 84.6 N.A. 40.1 42 34.3 49.1
Protein Similarity: 100 98.2 100 98.8 N.A. 98.6 73.8 N.A. 97.1 96.6 N.A. 91.6 N.A. 62.4 62.5 54.5 68.7
P-Site Identity: 100 100 100 100 N.A. 93.3 20 N.A. 100 93.3 N.A. 80 N.A. 40 20 20 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 40 N.A. 100 93.3 N.A. 93.3 N.A. 60 20 46.6 20
Percent
Protein Identity: N.A. N.A. N.A. 25.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 45.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 36 8 15 15 0 0 0 79 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58 % C
% Asp: 0 22 0 0 65 0 0 0 0 0 0 0 15 0 8 % D
% Glu: 0 0 72 8 8 8 0 0 0 0 0 0 65 8 15 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 65 0 0 0 0 0 0 72 8 8 8 0 % G
% His: 0 0 0 0 8 0 8 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 8 0 58 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 8 0 0 8 0 0 % K
% Leu: 93 0 0 0 0 65 0 0 8 0 22 15 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 8 0 0 0 15 0 0 0 0 0 % N
% Pro: 0 8 0 22 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 58 0 0 0 8 15 15 0 0 0 0 8 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 50 0 8 0 8 0 % R
% Ser: 0 0 8 8 15 0 15 65 50 8 8 8 0 0 8 % S
% Thr: 0 0 0 0 0 8 8 8 0 0 0 8 0 0 0 % T
% Val: 8 0 8 0 0 8 8 0 15 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _