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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOC1 All Species: 38.48
Human Site: S58 Identified Species: 65.13
UniProt: Q9NV70 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV70 NP_001020095.1 894 101982 S58 K V V K V K K S D K G D F Y K
Chimpanzee Pan troglodytes XP_001142521 886 101061 S58 K V V K V K K S D K G D F Y K
Rhesus Macaque Macaca mulatta XP_001087347 894 101935 S58 K V V K V K K S D K G D F Y K
Dog Lupus familis XP_532380 894 102004 S58 K M V K V K K S D K G D F Y K
Cat Felis silvestris
Mouse Mus musculus Q8R3S6 894 101859 S58 K V V K V K K S D K G D F Y K
Rat Rattus norvegicus NP_001019941 681 76652
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506171 894 101975 S58 N V V K V K K S D K G D F Y K
Chicken Gallus gallus XP_001232097 895 102211 S58 N V V K V K K S D K G D F Y K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_955891 892 101963 S58 K V V K V K K S D K G D F Y K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVG4 889 102677 S63 T L C L I K Q S E Q R E G E Y
Honey Bee Apis mellifera XP_396967 859 98113 N58 L L Y Q V K K N D K N V F K K
Nematode Worm Caenorhab. elegans Q20678 848 97279 E60 R L Y F V K G E K D D T F K K
Sea Urchin Strong. purpuratus XP_787291 869 100242 T58 C L H K V K K T D K D A Y K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SX85 887 100046 Y75 A F L R V M K Y S S G G V L E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 99.5 98.5 N.A. 97.1 70.9 N.A. 95 94 N.A. 84.6 N.A. 40.1 42 34.3 49.1
Protein Similarity: 100 98.2 100 98.8 N.A. 98.6 73.8 N.A. 97.1 96.6 N.A. 91.6 N.A. 62.4 62.5 54.5 68.7
P-Site Identity: 100 100 100 93.3 N.A. 100 0 N.A. 93.3 93.3 N.A. 100 N.A. 13.3 46.6 26.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 93.3 93.3 N.A. 100 N.A. 53.3 66.6 40 66.6
Percent
Protein Identity: N.A. N.A. N.A. 25.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 45.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 72 8 15 58 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 8 0 0 8 0 8 8 % E
% Phe: 0 8 0 8 0 0 0 0 0 0 0 0 72 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 65 8 8 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 43 0 0 65 0 86 79 0 8 72 0 0 0 22 79 % K
% Leu: 8 29 8 8 0 0 0 0 0 0 0 0 0 8 0 % L
% Met: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 8 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 65 8 8 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % T
% Val: 0 50 58 0 86 0 0 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 0 8 0 0 0 0 8 58 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _