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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM30A All Species: 15.45
Human Site: S280 Identified Species: 28.33
UniProt: Q9NV96 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NV96 NP_001137430.1 361 40684 S280 Y R L I E R K S D L H P T L P
Chimpanzee Pan troglodytes XP_001143816 473 53255 S392 Y R L I E R K S D L H P T L P
Rhesus Macaque Macaca mulatta XP_001109918 310 35027 T230 L E E R F K G T T K P V N W L
Dog Lupus familis XP_532208 361 40673 S280 Y R L I E R K S D L H P T L P
Cat Felis silvestris
Mouse Mus musculus Q8VEK0 364 41042 D283 Y R L I E R R D D L H P T L P
Rat Rattus norvegicus Q6AY41 328 37154 D248 R L I E R T D D L H P T L P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511750 410 46153 N329 Y R L I E K K N G L Q P T L P
Chicken Gallus gallus Q5F362 372 41430 S291 Y R L I E R K S N L Q P T L Q
Frog Xenopus laevis NP_001083672 364 40853 D283 Y R L I E K T D A T Y P A L E
Zebra Danio Brachydanio rerio NP_991123 368 41757 N287 Y R I I Q K K N N M T P T L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573128 357 39685 T270 R R L N Q T N T N Y A N G L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SLK2 349 38936 L265 Y G K I E S D L E M G D T I H
Baker's Yeast Sacchar. cerevisiae P25656 391 44964 K287 K F Y K L T L K N E S A S L P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.3 83.9 93.9 N.A. 88.1 81.4 N.A. 61.7 81.4 75 71.4 N.A. 54 N.A. N.A. N.A.
Protein Similarity: 100 76.3 84.7 96.6 N.A. 92.5 84.4 N.A. 67.8 86.2 81.3 81.2 N.A. 67.8 N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 86.6 0 N.A. 73.3 80 46.6 53.3 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 6.6 N.A. 86.6 86.6 60 93.3 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38.5 34.7 N.A.
Protein Similarity: N.A. N.A. N.A. 53.4 51.4 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 8 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 24 31 0 0 8 0 0 0 % D
% Glu: 0 8 8 8 62 0 0 0 8 8 0 0 0 0 8 % E
% Phe: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 8 0 8 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 31 0 0 0 8 % H
% Ile: 0 0 16 70 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 0 8 8 0 31 47 8 0 8 0 0 0 0 8 % K
% Leu: 8 8 62 0 8 0 8 8 8 47 0 0 8 77 8 % L
% Met: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 16 31 0 0 8 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 16 62 0 8 54 % P
% Gln: 0 0 0 0 16 0 0 0 0 0 16 0 0 0 8 % Q
% Arg: 16 70 0 8 8 39 8 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 8 0 31 0 0 8 0 8 0 0 % S
% Thr: 0 0 0 0 0 24 8 16 8 8 8 8 62 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 70 0 8 0 0 0 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _