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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UQCC All Species: 21.21
Human Site: S291 Identified Species: 42.42
UniProt: Q9NVA1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVA1 NP_060714.3 299 34572 S291 Q S I L K P H S P T Y N D E G
Chimpanzee Pan troglodytes XP_514604 299 34483 S291 Q S I L K P H S P T Y N D E G
Rhesus Macaque Macaca mulatta XP_001099909 298 34239 S290 Q S I L K P H S P T Y N D E G
Dog Lupus familis XP_851851 299 34633 S291 Q S I L K P H S P T Y N D E G
Cat Felis silvestris
Mouse Mus musculus Q9CWU6 295 34281 A287 Q S I L K P H A P T Y N D E G
Rat Rattus norvegicus NP_001102916 299 34528 A291 Q S I L K P H A P T Y N D E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006285 302 34325 S294 R S I L K P L S P V Y N D E G
Frog Xenopus laevis Q9W6I0 200 23354 P193 S I L K P S T P T Y N D E G L
Zebra Danio Brachydanio rerio NP_001070223 286 32798 S278 Q S I L K V P S P T Y N D T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648064 259 29416 L252 V K P K V A W L E L D K C K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175737 343 38828 K324 D S S E P L P K A A S L E D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P21560 335 39065 A316 K T I A K Y E A L D K D P K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 95.9 90.3 N.A. 86.9 86.2 N.A. N.A. 66.8 50.1 55.8 N.A. 30.4 N.A. N.A. 35.5
Protein Similarity: 100 99.6 96.6 93.9 N.A. 91.3 91.3 N.A. N.A. 77.1 58.1 73.2 N.A. 48.8 N.A. N.A. 53.3
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 80 0 80 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 20 80 N.A. 6.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 25 9 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 9 9 17 67 9 0 % D
% Glu: 0 0 0 9 0 0 9 0 9 0 0 0 17 59 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 67 % G
% His: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 75 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 0 17 75 0 0 9 0 0 9 9 0 17 0 % K
% Leu: 0 0 9 67 0 9 9 9 9 9 0 9 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 67 0 0 0 % N
% Pro: 0 0 9 0 17 59 17 9 67 0 0 0 9 0 0 % P
% Gln: 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 75 9 0 0 9 0 50 0 0 9 0 0 0 0 % S
% Thr: 0 9 0 0 0 0 9 0 9 59 0 0 0 9 9 % T
% Val: 9 0 0 0 9 9 0 0 0 9 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 9 67 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _