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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT11
All Species:
30
Human Site:
Y255
Identified Species:
60
UniProt:
Q9NVA2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVA2
NP_060713.1
429
49398
Y255
K
M
A
K
A
R
Q
Y
P
W
G
V
V
Q
V
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
Q263
G
K
R
V
R
G
R
Q
Y
P
W
G
V
A
E
Rhesus Macaque
Macaca mulatta
XP_001093263
417
48235
R266
H
C
D
F
V
K
L
R
E
M
L
I
R
V
N
Dog
Lupus familis
XP_535616
453
52093
Y279
K
M
A
K
A
R
Q
Y
P
W
G
V
V
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C1B7
431
49676
Y255
K
M
A
K
A
R
Q
Y
P
W
G
V
V
Q
V
Rat
Rattus norvegicus
B0BNF1
442
51234
Y258
K
L
V
R
A
R
Q
Y
P
W
G
V
V
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507217
668
75056
Y491
K
M
A
K
A
R
Q
Y
P
W
G
V
V
Q
V
Chicken
Gallus gallus
Q5ZMH1
349
40206
G249
N
Q
L
I
E
V
K
G
K
K
I
R
G
R
L
Frog
Xenopus laevis
Q6IRQ5
427
49743
Y256
K
L
V
R
A
R
Q
Y
P
W
G
V
V
Q
V
Zebra Danio
Brachydanio rerio
Q642H3
420
48980
Y256
K
T
V
R
A
R
Q
Y
P
W
G
V
V
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
Y257
K
L
I
R
A
R
Q
Y
P
W
G
T
V
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
R358
N
Y
S
G
N
Q
V
R
G
R
S
Y
P
W
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.8
97.1
93.3
N.A.
98.6
76.4
N.A.
61
36.3
79.7
79.9
N.A.
68.7
N.A.
N.A.
N.A.
Protein Similarity:
100
63.5
97.1
93.3
N.A.
98.8
86.4
N.A.
63.3
55.2
89
88.5
N.A.
80.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
100
N.A.
100
80
N.A.
100
0
80
80
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
93.3
N.A.
100
20
93.3
86.6
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
67
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
0
9
0
9
9
0
67
9
9
0
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
0
9
9
0
0
0
% I
% Lys:
67
9
0
34
0
9
9
0
9
9
0
0
0
0
0
% K
% Leu:
0
25
9
0
0
0
9
0
0
0
9
0
0
0
9
% L
% Met:
0
34
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
17
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
67
9
0
0
9
0
0
% P
% Gln:
0
9
0
0
0
9
67
9
0
0
0
0
0
67
0
% Q
% Arg:
0
0
9
34
9
67
9
17
0
9
0
9
9
9
0
% R
% Ser:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
25
9
9
9
9
0
0
0
0
59
75
9
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
67
9
0
0
9
0
% W
% Tyr:
0
9
0
0
0
0
0
67
9
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _