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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM184C
All Species:
40.91
Human Site:
S344
Identified Species:
75
UniProt:
Q9NVA4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVA4
NP_060711.2
438
50071
S344
S
D
I
R
D
D
I
S
E
Q
V
R
H
V
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099142
438
50199
S344
S
D
I
R
D
D
I
S
E
Q
V
R
H
V
G
Dog
Lupus familis
XP_532683
438
50177
S344
S
D
I
R
D
D
I
S
E
Q
V
R
H
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPR7
525
60025
S344
S
D
I
R
D
D
I
S
E
Q
V
R
R
V
G
Rat
Rattus norvegicus
Q810F5
503
57899
S344
S
D
I
R
E
D
I
S
E
Q
V
R
R
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510764
449
51209
S342
S
D
I
R
A
D
I
S
E
Q
V
R
N
V
G
Chicken
Gallus gallus
Q5ZMP3
445
50912
S342
S
D
I
R
A
D
I
S
E
Q
V
R
N
V
G
Frog
Xenopus laevis
Q6GQE1
444
50312
S340
S
D
I
R
A
D
I
S
E
Q
V
R
N
V
G
Zebra Danio
Brachydanio rerio
NP_001139068
447
50748
S342
S
D
I
R
A
D
I
S
E
Q
V
R
N
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036350
569
63678
T351
S
D
M
Q
E
D
V
T
E
H
L
G
V
V
G
Honey Bee
Apis mellifera
XP_624809
422
48101
V334
A
F
R
A
M
W
D
V
S
D
V
H
N
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780261
516
57479
S354
T
D
I
A
H
D
L
S
S
H
V
K
R
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36142
418
48738
D317
Y
Y
N
Y
R
N
F
D
P
E
A
M
D
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
95.8
N.A.
67
67.7
N.A.
82.4
84
77.2
72.9
N.A.
35.8
43.3
N.A.
30.4
Protein Similarity:
100
N.A.
99
97
N.A.
74.4
76.7
N.A.
89.9
90.7
88.2
83.2
N.A.
53.5
62.7
N.A.
50.3
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
86.6
86.6
86.6
86.6
N.A.
40
6.6
N.A.
33.3
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
N.A.
80
20
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
31
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
85
0
0
31
85
8
8
0
8
0
0
8
8
0
% D
% Glu:
0
0
0
0
16
0
0
0
77
8
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
77
% G
% His:
0
0
0
0
8
0
0
0
0
16
0
8
24
0
0
% H
% Ile:
0
0
77
0
0
0
70
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
8
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
0
0
0
39
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
70
0
0
0
0
0
% Q
% Arg:
0
0
8
70
8
0
0
0
0
0
0
70
24
0
0
% R
% Ser:
77
0
0
0
0
0
0
77
16
0
0
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
8
0
0
85
0
8
77
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _