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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM184C All Species: 26.06
Human Site: S374 Identified Species: 47.78
UniProt: Q9NVA4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVA4 NP_060711.2 438 50071 S374 Q D Q N E H T S L L S S S S Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099142 438 50199 S374 Q D Q N E H T S L L S S S S Q
Dog Lupus familis XP_532683 438 50177 S374 Q D Q N E H T S L L S S S S Q
Cat Felis silvestris
Mouse Mus musculus Q3TPR7 525 60025 S373 D P D H N E H S S L L S S S S
Rat Rattus norvegicus Q810F5 503 57899 H369 C F P G D P D H N E H S S L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510764 449 51209 S372 H E Q N E H T S L L S S S T Q
Chicken Gallus gallus Q5ZMP3 445 50912 S372 H E Q N E H T S L L S S S T Q
Frog Xenopus laevis Q6GQE1 444 50312 S370 P E Q N E H T S L L S S S T Q
Zebra Danio Brachydanio rerio NP_001139068 447 50748 G372 A N H D E N R G L L S A G S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036350 569 63678 L483 E S N D D Y A L L L G A G A G
Honey Bee Apis mellifera XP_624809 422 48101 R359 L S R R I R G R S A Y Q Q A W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780261 516 57479 T419 G Q P T G N G T V V K E N V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36142 418 48738 T344 L K H G L R F T D N G R N S Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 95.8 N.A. 67 67.7 N.A. 82.4 84 77.2 72.9 N.A. 35.8 43.3 N.A. 30.4
Protein Similarity: 100 N.A. 99 97 N.A. 74.4 76.7 N.A. 89.9 90.7 88.2 83.2 N.A. 53.5 62.7 N.A. 50.3
P-Site Identity: 100 N.A. 100 100 N.A. 33.3 13.3 N.A. 80 80 80 40 N.A. 13.3 0 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 40 20 N.A. 93.3 93.3 93.3 66.6 N.A. 53.3 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 8 0 0 8 0 16 0 16 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 24 8 16 16 0 8 0 8 0 0 0 0 0 0 % D
% Glu: 8 24 0 0 54 8 0 0 0 8 0 8 0 0 0 % E
% Phe: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 16 8 0 16 8 0 0 16 0 16 0 8 % G
% His: 16 0 16 8 0 47 8 8 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 16 0 0 0 8 0 0 8 62 70 8 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 47 8 16 0 0 8 8 0 0 16 0 0 % N
% Pro: 8 8 16 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 24 8 47 0 0 0 0 0 0 0 0 8 8 0 54 % Q
% Arg: 0 0 8 8 0 16 8 8 0 0 0 8 0 0 0 % R
% Ser: 0 16 0 0 0 0 0 54 16 0 54 62 62 47 8 % S
% Thr: 0 0 0 8 0 0 47 16 0 0 0 0 0 24 0 % T
% Val: 0 0 0 0 0 0 0 0 8 8 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _