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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM184C
All Species:
26.06
Human Site:
S374
Identified Species:
47.78
UniProt:
Q9NVA4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVA4
NP_060711.2
438
50071
S374
Q
D
Q
N
E
H
T
S
L
L
S
S
S
S
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099142
438
50199
S374
Q
D
Q
N
E
H
T
S
L
L
S
S
S
S
Q
Dog
Lupus familis
XP_532683
438
50177
S374
Q
D
Q
N
E
H
T
S
L
L
S
S
S
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPR7
525
60025
S373
D
P
D
H
N
E
H
S
S
L
L
S
S
S
S
Rat
Rattus norvegicus
Q810F5
503
57899
H369
C
F
P
G
D
P
D
H
N
E
H
S
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510764
449
51209
S372
H
E
Q
N
E
H
T
S
L
L
S
S
S
T
Q
Chicken
Gallus gallus
Q5ZMP3
445
50912
S372
H
E
Q
N
E
H
T
S
L
L
S
S
S
T
Q
Frog
Xenopus laevis
Q6GQE1
444
50312
S370
P
E
Q
N
E
H
T
S
L
L
S
S
S
T
Q
Zebra Danio
Brachydanio rerio
NP_001139068
447
50748
G372
A
N
H
D
E
N
R
G
L
L
S
A
G
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036350
569
63678
L483
E
S
N
D
D
Y
A
L
L
L
G
A
G
A
G
Honey Bee
Apis mellifera
XP_624809
422
48101
R359
L
S
R
R
I
R
G
R
S
A
Y
Q
Q
A
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780261
516
57479
T419
G
Q
P
T
G
N
G
T
V
V
K
E
N
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36142
418
48738
T344
L
K
H
G
L
R
F
T
D
N
G
R
N
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
95.8
N.A.
67
67.7
N.A.
82.4
84
77.2
72.9
N.A.
35.8
43.3
N.A.
30.4
Protein Similarity:
100
N.A.
99
97
N.A.
74.4
76.7
N.A.
89.9
90.7
88.2
83.2
N.A.
53.5
62.7
N.A.
50.3
P-Site Identity:
100
N.A.
100
100
N.A.
33.3
13.3
N.A.
80
80
80
40
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
40
20
N.A.
93.3
93.3
93.3
66.6
N.A.
53.3
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
8
0
16
0
16
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
24
8
16
16
0
8
0
8
0
0
0
0
0
0
% D
% Glu:
8
24
0
0
54
8
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
16
8
0
16
8
0
0
16
0
16
0
8
% G
% His:
16
0
16
8
0
47
8
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
16
0
0
0
8
0
0
8
62
70
8
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
47
8
16
0
0
8
8
0
0
16
0
0
% N
% Pro:
8
8
16
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
24
8
47
0
0
0
0
0
0
0
0
8
8
0
54
% Q
% Arg:
0
0
8
8
0
16
8
8
0
0
0
8
0
0
0
% R
% Ser:
0
16
0
0
0
0
0
54
16
0
54
62
62
47
8
% S
% Thr:
0
0
0
8
0
0
47
16
0
0
0
0
0
24
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _