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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM184C
All Species:
27.88
Human Site:
S385
Identified Species:
51.11
UniProt:
Q9NVA4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVA4
NP_060711.2
438
50071
S385
S
S
S
Q
D
A
I
S
I
A
S
S
M
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099142
438
50199
S385
S
S
S
Q
D
A
I
S
I
T
S
S
M
P
P
Dog
Lupus familis
XP_532683
438
50177
S385
S
S
S
Q
D
A
V
S
V
A
S
S
V
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPR7
525
60025
T384
S
S
S
S
Q
D
L
T
S
G
S
S
K
V
P
Rat
Rattus norvegicus
Q810F5
503
57899
S380
S
S
L
L
S
A
S
S
Q
D
S
S
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510764
449
51209
S383
S
S
T
Q
D
L
L
S
E
A
S
S
M
P
P
Chicken
Gallus gallus
Q5ZMP3
445
50912
S383
S
S
T
Q
D
P
I
S
D
A
S
S
M
P
S
Frog
Xenopus laevis
Q6GQE1
444
50312
S381
S
S
T
Q
D
P
I
S
A
A
S
S
I
P
P
Zebra Danio
Brachydanio rerio
NP_001139068
447
50748
I383
A
G
S
Q
D
A
A
I
E
S
S
S
T
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036350
569
63678
L494
A
G
A
G
S
A
S
L
S
V
S
F
G
M
S
Honey Bee
Apis mellifera
XP_624809
422
48101
T370
Q
Q
A
W
G
S
A
T
E
R
T
S
L
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780261
516
57479
A430
E
N
V
V
D
A
G
A
D
N
K
V
F
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36142
418
48738
Y355
R
N
S
Y
W
V
A
Y
G
S
I
D
N
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
95.8
N.A.
67
67.7
N.A.
82.4
84
77.2
72.9
N.A.
35.8
43.3
N.A.
30.4
Protein Similarity:
100
N.A.
99
97
N.A.
74.4
76.7
N.A.
89.9
90.7
88.2
83.2
N.A.
53.5
62.7
N.A.
50.3
P-Site Identity:
100
N.A.
93.3
80
N.A.
40
46.6
N.A.
73.3
73.3
73.3
53.3
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
93.3
100
N.A.
53.3
46.6
N.A.
86.6
80
86.6
66.6
N.A.
26.6
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
0
0
54
24
8
8
39
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
62
8
0
0
16
8
0
8
0
8
0
% D
% Glu:
8
0
0
0
0
0
0
0
24
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% F
% Gly:
0
16
0
8
8
0
8
0
8
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
31
8
16
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
16
0
0
% K
% Leu:
0
0
8
8
0
8
16
8
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
31
8
0
% M
% Asn:
0
16
0
0
0
0
0
0
0
8
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
0
0
0
0
62
62
% P
% Gln:
8
8
0
54
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
62
62
47
8
16
8
16
54
16
16
77
77
0
0
24
% S
% Thr:
0
0
24
0
0
0
0
16
0
8
8
0
8
0
0
% T
% Val:
0
0
8
8
0
8
8
0
8
8
0
8
8
8
0
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _