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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM184C All Species: 32.12
Human Site: T406 Identified Species: 58.89
UniProt: Q9NVA4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVA4 NP_060711.2 438 50071 T406 Q G F G H T V T P Q T T P T T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099142 438 50199 T406 Q G F G H T V T P Q T T P T T
Dog Lupus familis XP_532683 438 50177 T406 Q G F G H T V T P Q T T P T T
Cat Felis silvestris
Mouse Mus musculus Q3TPR7 525 60025 S405 Q G F G H T I S S Q S P I S I
Rat Rattus norvegicus Q810F5 503 57899 T401 Q G F G Q T I T S Q S P I S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510764 449 51209 T404 Q G F G H T V T P Q T T P T A
Chicken Gallus gallus Q5ZMP3 445 50912 T404 Q G F G H T V T P L T T P T T
Frog Xenopus laevis Q6GQE1 444 50312 T402 Q G F G Q T I T P Q T T P T A
Zebra Danio Brachydanio rerio NP_001139068 447 50748 T404 Q G M G H T V T P H S I S A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036350 569 63678 A515 A T G S N Q S A S E W S N S T
Honey Bee Apis mellifera XP_624809 422 48101 S391 A R S A P A C S F S G Y N T A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780261 516 57479 S451 S N G T E T R S V L H D S R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36142 418 48738 A376 E S W E D D I A G Q R T F P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 95.8 N.A. 67 67.7 N.A. 82.4 84 77.2 72.9 N.A. 35.8 43.3 N.A. 30.4
Protein Similarity: 100 N.A. 99 97 N.A. 74.4 76.7 N.A. 89.9 90.7 88.2 83.2 N.A. 53.5 62.7 N.A. 50.3
P-Site Identity: 100 N.A. 100 100 N.A. 46.6 46.6 N.A. 93.3 93.3 80 53.3 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 73.3 66.6 N.A. 93.3 93.3 86.6 60 N.A. 33.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 0 8 0 16 0 0 0 0 0 8 24 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 0 0 8 0 0 0 % D
% Glu: 8 0 0 8 8 0 0 0 0 8 0 0 0 0 8 % E
% Phe: 0 0 62 0 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 0 70 16 70 0 0 0 0 8 0 8 0 0 0 0 % G
% His: 0 0 0 0 54 0 0 0 0 8 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 31 0 0 0 0 8 16 0 16 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 0 0 0 16 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 54 0 0 16 47 8 8 % P
% Gln: 70 0 0 0 16 8 0 0 0 62 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 8 0 0 0 8 0 0 8 0 % R
% Ser: 8 8 8 8 0 0 8 24 24 8 24 8 16 24 8 % S
% Thr: 0 8 0 8 0 77 0 62 0 0 47 54 0 54 39 % T
% Val: 0 0 0 0 0 0 47 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _