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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM184C
All Species:
22.42
Human Site:
T410
Identified Species:
41.11
UniProt:
Q9NVA4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVA4
NP_060711.2
438
50071
T410
H
T
V
T
P
Q
T
T
P
T
T
A
K
I
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099142
438
50199
T410
H
T
V
T
P
Q
T
T
P
T
T
S
K
I
S
Dog
Lupus familis
XP_532683
438
50177
T410
H
T
V
T
P
Q
T
T
P
T
T
A
N
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPR7
525
60025
P409
H
T
I
S
S
Q
S
P
I
S
I
A
S
I
Y
Rat
Rattus norvegicus
Q810F5
503
57899
P405
Q
T
I
T
S
Q
S
P
I
S
I
A
N
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510764
449
51209
T408
H
T
V
T
P
Q
T
T
P
T
A
A
G
M
P
Chicken
Gallus gallus
Q5ZMP3
445
50912
T408
H
T
V
T
P
L
T
T
P
T
T
V
P
V
V
Frog
Xenopus laevis
Q6GQE1
444
50312
T406
Q
T
I
T
P
Q
T
T
P
T
A
A
T
I
P
Zebra Danio
Brachydanio rerio
NP_001139068
447
50748
I408
H
T
V
T
P
H
S
I
S
A
P
A
N
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036350
569
63678
S519
N
Q
S
A
S
E
W
S
N
S
T
G
G
D
N
Honey Bee
Apis mellifera
XP_624809
422
48101
Y395
P
A
C
S
F
S
G
Y
N
T
A
E
I
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780261
516
57479
D455
E
T
R
S
V
L
H
D
S
R
S
Y
L
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36142
418
48738
T380
D
D
I
A
G
Q
R
T
F
P
E
D
P
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
95.8
N.A.
67
67.7
N.A.
82.4
84
77.2
72.9
N.A.
35.8
43.3
N.A.
30.4
Protein Similarity:
100
N.A.
99
97
N.A.
74.4
76.7
N.A.
89.9
90.7
88.2
83.2
N.A.
53.5
62.7
N.A.
50.3
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
33.3
26.6
N.A.
73.3
66.6
66.6
40
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
60
53.3
N.A.
80
73.3
73.3
53.3
N.A.
40
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
0
0
0
0
0
8
24
54
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
8
0
0
0
8
0
8
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
0
8
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
0
0
0
8
16
0
8
% G
% His:
54
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
31
0
0
0
0
8
16
0
16
0
8
39
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% K
% Leu:
0
0
0
0
0
16
0
0
0
0
0
0
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
0
0
16
0
0
0
24
8
16
% N
% Pro:
8
0
0
0
54
0
0
16
47
8
8
0
16
0
16
% P
% Gln:
16
8
0
0
0
62
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
8
0
0
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
24
24
8
24
8
16
24
8
8
8
0
16
% S
% Thr:
0
77
0
62
0
0
47
54
0
54
39
0
8
0
0
% T
% Val:
0
0
47
0
8
0
0
0
0
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _