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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM184C
All Species:
10.91
Human Site:
T424
Identified Species:
20
UniProt:
Q9NVA4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVA4
NP_060711.2
438
50071
T424
S
D
E
I
L
S
D
T
I
G
E
K
K
E
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099142
438
50199
T424
S
D
E
I
L
S
D
T
I
G
E
K
K
E
P
Dog
Lupus familis
XP_532683
438
50177
T424
A
D
E
I
C
N
D
T
T
E
E
K
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TPR7
525
60025
I423
Y
E
E
I
M
N
D
I
P
E
E
Q
Q
K
L
Rat
Rattus norvegicus
Q810F5
503
57899
I419
Y
E
E
I
L
N
E
I
P
E
E
Q
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510764
449
51209
A422
P
A
G
I
Y
S
S
A
A
E
E
N
G
D
S
Chicken
Gallus gallus
Q5ZMP3
445
50912
S422
V
D
G
I
Y
N
T
S
A
T
R
D
T
E
E
Frog
Xenopus laevis
Q6GQE1
444
50312
D420
P
E
E
L
Y
S
A
D
S
P
E
A
D
L
Q
Zebra Danio
Brachydanio rerio
NP_001139068
447
50748
D422
G
C
V
P
W
E
G
D
V
D
D
I
P
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036350
569
63678
L533
N
D
A
D
D
G
D
L
D
V
D
G
E
D
G
Honey Bee
Apis mellifera
XP_624809
422
48101
L409
Q
N
D
G
T
I
D
L
I
P
D
V
Q
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780261
516
57479
N469
N
D
N
G
L
I
G
N
D
D
D
L
G
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36142
418
48738
T394
Y
P
V
V
H
D
Y
T
M
G
H
R
Y
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
95.8
N.A.
67
67.7
N.A.
82.4
84
77.2
72.9
N.A.
35.8
43.3
N.A.
30.4
Protein Similarity:
100
N.A.
99
97
N.A.
74.4
76.7
N.A.
89.9
90.7
88.2
83.2
N.A.
53.5
62.7
N.A.
50.3
P-Site Identity:
100
N.A.
100
60
N.A.
26.6
26.6
N.A.
20
20
20
0
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
100
73.3
N.A.
66.6
60
N.A.
26.6
33.3
33.3
13.3
N.A.
40
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
8
8
16
0
0
8
0
0
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
8
8
8
8
47
16
16
16
31
8
8
24
0
% D
% Glu:
0
24
47
0
0
8
8
0
0
31
54
0
8
31
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
16
0
8
16
0
0
24
0
8
16
8
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
54
0
16
0
16
24
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
24
24
8
0
% K
% Leu:
0
0
0
8
31
0
0
16
0
0
0
8
0
8
24
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
16
8
8
0
0
31
0
8
0
0
0
8
0
0
0
% N
% Pro:
16
8
0
8
0
0
0
0
16
16
0
0
8
8
16
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
16
24
0
16
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
8
% R
% Ser:
16
0
0
0
0
31
8
8
8
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
8
0
8
31
8
8
0
0
8
0
16
% T
% Val:
8
0
16
8
0
0
0
0
8
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
0
0
24
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _