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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED17
All Species:
45.76
Human Site:
S344
Identified Species:
83.89
UniProt:
Q9NVC6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVC6
NP_004259.3
651
72876
S344
P
S
L
Q
L
S
I
S
L
C
H
S
S
N
D
Chimpanzee
Pan troglodytes
XP_508698
829
93185
S522
P
S
L
Q
L
S
I
S
L
C
H
S
S
N
D
Rhesus Macaque
Macaca mulatta
XP_001088365
651
72869
S344
P
N
L
Q
L
S
I
S
L
C
H
S
S
N
D
Dog
Lupus familis
XP_533975
766
84626
S459
P
S
L
Q
L
L
I
S
L
C
H
S
S
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCD5
649
72443
S342
P
S
L
Q
L
S
I
S
L
C
H
S
S
D
D
Rat
Rattus norvegicus
NP_001100271
649
72425
S342
P
S
L
Q
L
S
I
S
L
C
H
S
S
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512596
653
73060
S347
P
G
L
Q
L
S
I
S
L
C
H
S
S
N
D
Chicken
Gallus gallus
Q5ZID1
643
72111
S338
P
G
L
Q
L
S
I
S
L
C
H
S
S
N
D
Frog
Xenopus laevis
NP_001093376
640
72297
S335
P
G
L
Q
L
S
I
S
L
C
H
S
S
N
D
Zebra Danio
Brachydanio rerio
Q08BY1
643
72306
S337
P
G
L
Q
L
S
I
S
L
C
H
S
T
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC1
642
71538
S341
P
N
I
Q
L
I
I
S
L
C
H
S
T
T
F
Honey Bee
Apis mellifera
XP_394516
644
71969
G344
P
G
I
Q
L
I
I
G
L
C
H
S
T
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783830
984
110041
T333
H
G
V
Q
L
C
I
T
L
C
H
D
T
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
99.2
82.1
N.A.
95.5
95.8
N.A.
89.8
89.8
84
79.1
N.A.
43.4
44.5
N.A.
29.7
Protein Similarity:
100
78.5
99.6
83.4
N.A.
97.6
97.8
N.A.
94.1
94.4
91.2
88.6
N.A.
64.8
65.4
N.A.
43.1
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
73.3
N.A.
60
53.3
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
80
73.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
100
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
16
70
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
47
0
0
0
0
0
8
0
0
0
0
0
16
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% H
% Ile:
0
0
16
0
0
16
100
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
77
0
100
8
0
0
100
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
16
0
0
0
0
0
0
0
0
0
0
0
62
8
% N
% Pro:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
39
0
0
0
70
0
85
0
0
0
93
70
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
31
8
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _