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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED17
All Species:
17.88
Human Site:
T168
Identified Species:
32.78
UniProt:
Q9NVC6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVC6
NP_004259.3
651
72876
T168
L
K
G
A
E
R
L
T
K
S
V
T
E
N
Q
Chimpanzee
Pan troglodytes
XP_508698
829
93185
T346
L
K
G
A
E
R
L
T
K
S
V
T
E
N
Q
Rhesus Macaque
Macaca mulatta
XP_001088365
651
72869
T168
L
K
G
A
E
R
L
T
K
S
V
T
E
N
Q
Dog
Lupus familis
XP_533975
766
84626
T283
L
K
G
A
E
R
L
T
K
S
V
T
E
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCD5
649
72443
N172
L
T
K
S
V
A
E
N
Q
E
N
K
L
Q
R
Rat
Rattus norvegicus
NP_001100271
649
72425
N172
L
T
K
S
V
T
E
N
Q
E
N
K
L
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512596
653
73060
T171
L
K
G
A
D
R
L
T
K
S
V
A
E
N
Q
Chicken
Gallus gallus
Q5ZID1
643
72111
N168
L
S
K
S
V
A
E
N
Q
E
N
K
R
Q
R
Frog
Xenopus laevis
NP_001093376
640
72297
E167
K
S
V
A
E
N
Q
E
N
K
R
Q
R
D
F
Zebra Danio
Brachydanio rerio
Q08BY1
643
72306
E170
K
S
V
S
E
N
Q
E
Q
R
R
Q
R
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC1
642
71538
I168
R
N
V
S
D
F
H
I
E
L
L
R
L
R
Q
Honey Bee
Apis mellifera
XP_394516
644
71969
I169
R
S
T
P
D
F
H
I
E
L
L
R
L
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783830
984
110041
L420
I
Q
Q
T
E
C
L
L
E
K
I
M
K
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
99.2
82.1
N.A.
95.5
95.8
N.A.
89.8
89.8
84
79.1
N.A.
43.4
44.5
N.A.
29.7
Protein Similarity:
100
78.5
99.6
83.4
N.A.
97.6
97.8
N.A.
94.1
94.4
91.2
88.6
N.A.
64.8
65.4
N.A.
43.1
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
86.6
6.6
13.3
6.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
93.3
26.6
20
26.6
N.A.
33.3
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
47
0
16
0
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
24
0
0
0
0
0
0
0
0
16
0
% D
% Glu:
0
0
0
0
54
0
24
16
24
24
0
0
39
0
0
% E
% Phe:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
16
0
0
8
0
0
0
0
% I
% Lys:
16
39
24
0
0
0
0
0
39
16
0
24
8
0
0
% K
% Leu:
62
0
0
0
0
0
47
8
0
16
16
0
31
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
16
0
24
8
0
24
0
0
39
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
16
0
31
0
0
16
0
31
54
% Q
% Arg:
16
0
0
0
0
39
0
0
0
8
16
16
24
16
24
% R
% Ser:
0
31
0
39
0
0
0
0
0
39
0
0
0
0
0
% S
% Thr:
0
16
8
8
0
8
0
39
0
0
0
31
0
0
0
% T
% Val:
0
0
24
0
24
0
0
0
0
0
39
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _