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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED17
All Species:
45.45
Human Site:
Y256
Identified Species:
83.33
UniProt:
Q9NVC6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVC6
NP_004259.3
651
72876
Y256
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Chimpanzee
Pan troglodytes
XP_508698
829
93185
Y434
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Rhesus Macaque
Macaca mulatta
XP_001088365
651
72869
Y256
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Dog
Lupus familis
XP_533975
766
84626
Y371
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCD5
649
72443
Y254
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Rat
Rattus norvegicus
NP_001100271
649
72425
Y254
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512596
653
73060
Y259
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Chicken
Gallus gallus
Q5ZID1
643
72111
Y250
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Frog
Xenopus laevis
NP_001093376
640
72297
Y247
S
D
L
E
G
S
A
Y
L
K
V
S
I
Q
K
Zebra Danio
Brachydanio rerio
Q08BY1
643
72306
Y250
S
D
L
E
G
S
A
Y
I
K
V
S
I
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC1
642
71538
Y255
A
E
L
Q
G
V
A
Y
I
K
V
I
T
Q
K
Honey Bee
Apis mellifera
XP_394516
644
71969
V256
I
P
S
E
L
Q
G
V
A
Y
I
E
V
L
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783830
984
110041
T247
I
P
S
D
L
Q
G
T
S
Y
I
Q
V
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
99.2
82.1
N.A.
95.5
95.8
N.A.
89.8
89.8
84
79.1
N.A.
43.4
44.5
N.A.
29.7
Protein Similarity:
100
78.5
99.6
83.4
N.A.
97.6
97.8
N.A.
94.1
94.4
91.2
88.6
N.A.
64.8
65.4
N.A.
43.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
60
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
80
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
85
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
77
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
85
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
85
0
16
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
77
0
16
8
77
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
85
0
0
0
0
85
% K
% Leu:
0
0
85
0
16
0
0
0
8
0
0
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
16
0
0
0
0
0
8
0
85
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
77
0
16
0
0
77
0
0
8
0
0
77
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
8
0
0
85
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _