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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED17
All Species:
36.67
Human Site:
Y369
Identified Species:
67.22
UniProt:
Q9NVC6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVC6
NP_004259.3
651
72876
Y369
Q
C
P
E
D
H
L
Y
V
L
E
H
N
L
H
Chimpanzee
Pan troglodytes
XP_508698
829
93185
Y547
Q
C
P
E
D
H
L
Y
V
L
E
H
N
L
H
Rhesus Macaque
Macaca mulatta
XP_001088365
651
72869
Y369
Q
C
P
E
D
H
L
Y
V
L
E
H
N
L
H
Dog
Lupus familis
XP_533975
766
84626
Y484
Q
S
P
E
D
H
L
Y
V
L
E
H
N
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCD5
649
72443
Y367
P
G
Q
E
D
H
L
Y
V
L
E
H
N
L
H
Rat
Rattus norvegicus
NP_001100271
649
72425
Y367
P
G
Q
E
G
H
L
Y
V
L
E
H
N
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512596
653
73060
Y372
Q
T
P
E
D
H
L
Y
V
L
E
H
N
L
H
Chicken
Gallus gallus
Q5ZID1
643
72111
Y363
Q
N
P
E
G
H
L
Y
V
L
E
H
N
L
H
Frog
Xenopus laevis
NP_001093376
640
72297
Y360
V
G
A
E
D
H
L
Y
V
L
E
H
N
L
H
Zebra Danio
Brachydanio rerio
Q08BY1
643
72306
Y362
S
K
P
D
D
H
L
Y
V
L
E
H
N
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEC1
642
71538
S366
H
D
H
V
L
E
H
S
L
H
Q
L
L
R
E
Honey Bee
Apis mellifera
XP_394516
644
71969
L369
K
S
E
H
D
H
V
L
E
H
S
L
H
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783830
984
110041
K695
Q
Y
I
E
G
A
V
K
P
N
H
S
H
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
99.2
82.1
N.A.
95.5
95.8
N.A.
89.8
89.8
84
79.1
N.A.
43.4
44.5
N.A.
29.7
Protein Similarity:
100
78.5
99.6
83.4
N.A.
97.6
97.8
N.A.
94.1
94.4
91.2
88.6
N.A.
64.8
65.4
N.A.
43.1
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
93.3
86.6
80
80
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
80
73.3
N.A.
93.3
86.6
80
86.6
N.A.
13.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
70
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
77
0
8
0
0
8
0
77
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
24
0
0
24
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
8
8
0
85
8
0
0
16
8
77
16
0
77
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
77
8
8
77
0
16
8
77
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
77
0
0
% N
% Pro:
16
0
54
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
54
0
16
0
0
0
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
16
0
0
0
0
0
8
0
0
8
8
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
16
0
77
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _