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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARVA
All Species:
21.52
Human Site:
S174
Identified Species:
39.44
UniProt:
Q9NVD7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVD7
NP_060692.1
372
42244
S174
T
L
K
L
P
P
R
S
I
K
W
N
V
D
S
Chimpanzee
Pan troglodytes
XP_001171467
372
42228
S174
T
L
K
L
P
P
R
S
I
K
W
N
V
D
S
Rhesus Macaque
Macaca mulatta
XP_001091788
385
43610
Q178
T
T
G
P
K
L
A
Q
P
S
Q
W
V
D
S
Dog
Lupus familis
XP_534062
411
46336
A162
A
L
S
Q
Y
F
R
A
P
I
R
L
P
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPC1
372
42311
S174
T
L
K
L
P
P
R
S
I
K
W
N
V
D
S
Rat
Rattus norvegicus
Q9HB97
372
42273
S174
A
L
K
L
P
P
R
S
I
K
W
N
V
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420963
376
42651
S178
T
L
K
L
P
P
R
S
I
K
W
N
V
D
S
Frog
Xenopus laevis
NP_001089519
365
41596
A167
L
L
R
P
Q
G
W
A
I
R
W
N
V
D
S
Zebra Danio
Brachydanio rerio
NP_001002872
372
42289
S174
A
L
K
V
S
T
R
S
I
K
W
N
V
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608352
367
41845
I169
T
L
G
F
H
Q
K
I
P
K
W
S
V
A
S
Honey Bee
Apis mellifera
XP_393249
365
41734
P167
R
V
L
G
R
Y
P
P
Y
K
W
H
V
E
S
Nematode Worm
Caenorhab. elegans
O16785
375
42983
Q178
I
L
G
Q
P
R
E
Q
E
K
W
S
A
D
L
Sea Urchin
Strong. purpuratus
XP_785434
360
41100
K162
L
N
L
P
R
W
N
K
D
K
W
S
V
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
84.9
75.9
N.A.
98.3
98.6
N.A.
N.A.
96.5
73.1
90.5
N.A.
55.9
61.2
48.7
56.4
Protein Similarity:
100
99.7
88.3
78.5
N.A.
99.1
99.1
N.A.
N.A.
97.6
86.2
96.2
N.A.
72.8
77.4
66.1
76.3
P-Site Identity:
100
100
26.6
20
N.A.
100
93.3
N.A.
N.A.
100
46.6
73.3
N.A.
40
26.6
33.3
26.6
P-Site Similarity:
100
100
26.6
26.6
N.A.
100
93.3
N.A.
N.A.
100
66.6
80
N.A.
53.3
46.6
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
0
0
0
8
16
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
85
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
24
8
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
8
54
8
0
0
0
0
0
% I
% Lys:
0
0
47
0
8
0
8
8
0
77
0
0
0
0
0
% K
% Leu:
16
77
16
39
0
8
0
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
54
0
0
0
% N
% Pro:
0
0
0
24
47
39
8
8
24
0
0
0
8
0
0
% P
% Gln:
0
0
0
16
8
8
0
16
0
0
8
0
0
0
0
% Q
% Arg:
8
0
8
0
16
8
54
0
0
8
8
0
0
0
0
% R
% Ser:
0
0
8
0
8
0
0
47
0
8
0
24
0
0
77
% S
% Thr:
47
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
8
0
0
0
0
0
0
0
0
85
0
0
% V
% Trp:
0
0
0
0
0
8
8
0
0
0
85
8
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _