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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARVA All Species: 23.33
Human Site: S19 Identified Species: 42.78
UniProt: Q9NVD7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVD7 NP_060692.1 372 42244 S19 P K S P T P K S P P S R K K D
Chimpanzee Pan troglodytes XP_001171467 372 42228 S19 X K S P T P K S P P S R K K D
Rhesus Macaque Macaca mulatta XP_001091788 385 43610 S19 P K S P T P K S P P S R K K D
Dog Lupus familis XP_534062 411 46336 I23 I N L P L S P I P F E L D P E
Cat Felis silvestris
Mouse Mus musculus Q9EPC1 372 42311 S19 P K S P T P K S P P S R K K D
Rat Rattus norvegicus Q9HB97 372 42273 S19 P K S P T P K S P P S R K K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420963 376 42651 R23 T P K S P P S R K K D K A F L
Frog Xenopus laevis NP_001089519 365 41596 D19 Q G Q K M K K D E S F L G K L
Zebra Danio Brachydanio rerio NP_001002872 372 42289 S19 P K S P T P K S P S S R K K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608352 367 41845 K21 T A I K K G E K E D S F W D K
Honey Bee Apis mellifera XP_393249 365 41734 E19 P I S A R K D E K E E S F W D
Nematode Worm Caenorhab. elegans O16785 375 42983 T27 V F E K L S G T L S R K K K A
Sea Urchin Strong. purpuratus XP_785434 360 41100 V24 E E S F L D K V T T L G R K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 84.9 75.9 N.A. 98.3 98.6 N.A. N.A. 96.5 73.1 90.5 N.A. 55.9 61.2 48.7 56.4
Protein Similarity: 100 99.7 88.3 78.5 N.A. 99.1 99.1 N.A. N.A. 97.6 86.2 96.2 N.A. 72.8 77.4 66.1 76.3
P-Site Identity: 100 93.3 100 13.3 N.A. 100 100 N.A. N.A. 6.6 13.3 93.3 N.A. 6.6 20 13.3 20
P-Site Similarity: 100 93.3 100 20 N.A. 100 100 N.A. N.A. 13.3 13.3 93.3 N.A. 13.3 20 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 0 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 8 0 8 8 0 8 8 54 % D
% Glu: 8 8 8 0 0 0 8 8 16 8 16 0 0 0 8 % E
% Phe: 0 8 0 8 0 0 0 0 0 8 8 8 8 8 0 % F
% Gly: 0 8 0 0 0 8 8 0 0 0 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 47 8 24 8 16 62 8 16 8 0 16 54 70 16 % K
% Leu: 0 0 8 0 24 0 0 0 8 0 8 16 0 0 16 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 47 8 0 54 8 54 8 0 54 39 0 0 0 8 0 % P
% Gln: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 8 0 0 8 47 8 0 0 % R
% Ser: 0 0 62 8 0 16 8 47 0 24 54 8 0 0 0 % S
% Thr: 16 0 0 0 47 0 0 8 8 8 0 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _