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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D13
All Species:
33.94
Human Site:
Y256
Identified Species:
62.22
UniProt:
Q9NVG8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVG8
NP_060671
275
32171
Y256
N
M
R
L
L
Q
D
Y
P
I
T
D
V
C
Q
Chimpanzee
Pan troglodytes
XP_520299
400
46507
Y381
N
M
R
L
L
Q
D
Y
P
I
T
D
V
C
Q
Rhesus Macaque
Macaca mulatta
XP_001118728
400
46540
Y381
N
M
R
L
L
Q
D
Y
P
I
T
D
V
C
Q
Dog
Lupus familis
XP_537821
429
49443
Y410
N
M
R
L
L
Q
D
Y
P
I
T
D
V
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3D1
400
46434
Y381
N
M
R
L
L
Q
D
Y
P
I
T
D
V
C
Q
Rat
Rattus norvegicus
XP_575106
400
46458
Y381
N
M
R
L
L
Q
D
Y
P
I
S
D
V
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516751
365
42205
W304
K
L
V
R
R
R
L
W
A
V
S
G
G
L
R
Chicken
Gallus gallus
XP_001233464
399
46466
Y380
N
M
R
L
L
Q
D
Y
P
I
S
D
V
H
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107894
414
48470
Y381
N
M
R
L
L
Q
D
Y
P
I
S
D
V
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648245
403
45850
N375
Q
R
E
A
I
L
E
N
D
F
A
S
N
V
K
Honey Bee
Apis mellifera
XP_392146
396
45583
F373
N
V
K
L
L
Q
N
F
P
S
M
D
I
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785171
321
37357
Y301
N
I
K
M
L
Q
H
Y
P
A
I
D
M
H
E
Poplar Tree
Populus trichocarpa
XP_002300164
356
40796
G328
I
R
R
R
L
L
A
G
D
F
T
S
I
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.5
68.2
61.3
N.A.
66.7
65.7
N.A.
49.8
60.6
N.A.
49.7
N.A.
37.2
41.1
N.A.
26.4
Protein Similarity:
100
68.7
68.7
62.9
N.A.
67.7
67.5
N.A.
58.3
65.6
N.A.
58.4
N.A.
51.6
53.2
N.A.
47
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
0
80
N.A.
80
N.A.
0
40
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
86.6
N.A.
86.6
N.A.
20
73.3
N.A.
73.3
Percent
Protein Identity:
33.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
50
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
8
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% C
% Asp:
0
0
0
0
0
0
62
0
16
0
0
77
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
16
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
24
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
62
8
0
16
0
8
% I
% Lys:
8
0
16
0
0
0
0
0
0
0
0
0
0
0
24
% K
% Leu:
0
8
0
70
85
16
8
0
0
0
0
0
0
16
8
% L
% Met:
0
62
0
8
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
77
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
77
0
0
0
0
0
0
0
8
39
% Q
% Arg:
0
16
70
16
8
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
31
16
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% T
% Val:
0
8
8
0
0
0
0
0
0
8
0
0
62
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _