KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXD2
All Species:
4.55
Human Site:
S151
Identified Species:
12.5
UniProt:
Q9NVH0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVH0
NP_060669.1
496
56346
S151
E
K
N
D
D
H
S
S
W
R
K
V
L
E
K
Chimpanzee
Pan troglodytes
XP_510030
621
70314
S276
E
K
N
D
D
H
S
S
W
R
K
V
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001108714
620
70262
W276
E
K
N
D
H
S
S
W
R
K
V
L
E
K
C
Dog
Lupus familis
XP_547872
623
70840
G278
D
G
Y
N
D
H
I
G
W
R
K
V
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEG4
496
56767
N151
E
E
S
T
D
Q
I
N
W
Q
K
A
L
E
R
Rat
Rattus norvegicus
NP_001102185
648
74041
N303
E
E
N
N
G
Q
I
N
W
Q
K
V
L
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421185
621
69329
W278
G
E
N
S
V
S
G
W
E
K
V
L
S
K
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650075
583
66848
A167
L
R
F
L
C
V
M
A
G
H
K
P
E
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797941
531
61217
K174
W
E
A
V
P
L
S
K
E
Q
I
H
Y
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
78.3
74.1
N.A.
87.5
68
N.A.
N.A.
60
N.A.
N.A.
N.A.
30
N.A.
N.A.
34.4
Protein Similarity:
100
79.5
79.1
77
N.A.
94.1
73.3
N.A.
N.A.
68.7
N.A.
N.A.
N.A.
49.7
N.A.
N.A.
50.6
P-Site Identity:
100
100
33.3
60
N.A.
40
53.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
53.3
73.3
N.A.
73.3
80
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
12
0
0
0
12
0
12
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
23
% C
% Asp:
12
0
0
34
45
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
56
45
0
0
0
0
0
0
23
0
0
0
23
56
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
0
12
0
12
12
12
0
0
0
0
12
0
% G
% His:
0
0
0
0
12
34
0
0
0
12
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
0
0
0
12
0
0
0
0
% I
% Lys:
0
34
0
0
0
0
0
12
0
23
67
0
0
23
45
% K
% Leu:
12
0
0
12
0
12
0
0
0
0
0
23
56
0
12
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
56
23
0
0
0
23
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
23
0
0
0
34
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
12
34
0
0
0
0
12
% R
% Ser:
0
0
12
12
0
23
45
23
0
0
0
0
12
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
12
12
0
0
0
0
23
45
0
0
12
% V
% Trp:
12
0
0
0
0
0
0
23
56
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _