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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXD2
All Species:
26.67
Human Site:
S449
Identified Species:
73.33
UniProt:
Q9NVH0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVH0
NP_060669.1
496
56346
S449
H
S
Q
G
G
L
R
S
L
M
Q
L
E
S
R
Chimpanzee
Pan troglodytes
XP_510030
621
70314
S574
H
S
Q
G
G
L
R
S
L
M
Q
L
E
S
R
Rhesus Macaque
Macaca mulatta
XP_001108714
620
70262
S573
H
S
Q
G
G
L
R
S
L
M
Q
L
E
S
R
Dog
Lupus familis
XP_547872
623
70840
S576
H
S
Q
G
G
L
R
S
L
M
Q
L
E
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEG4
496
56767
S449
H
T
E
G
G
L
R
S
L
M
Q
L
E
S
R
Rat
Rattus norvegicus
NP_001102185
648
74041
S601
H
T
E
G
G
L
R
S
L
M
Q
L
E
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421185
621
69329
S574
C
A
K
G
G
L
R
S
L
M
Q
L
E
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650075
583
66848
G523
Q
Y
R
D
H
F
G
G
L
V
E
L
E
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797941
531
61217
E490
V
V
E
E
V
M
K
E
E
S
G
L
R
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
78.3
74.1
N.A.
87.5
68
N.A.
N.A.
60
N.A.
N.A.
N.A.
30
N.A.
N.A.
34.4
Protein Similarity:
100
79.5
79.1
77
N.A.
94.1
73.3
N.A.
N.A.
68.7
N.A.
N.A.
N.A.
49.7
N.A.
N.A.
50.6
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
40
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
34
12
0
0
0
12
12
0
12
0
89
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
78
78
0
12
12
0
0
12
0
0
0
0
% G
% His:
67
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
12
0
0
0
0
0
0
12
0
% K
% Leu:
0
0
0
0
0
78
0
0
89
0
0
100
0
0
12
% L
% Met:
0
0
0
0
0
12
0
0
0
78
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
45
0
0
0
0
0
0
0
78
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
78
0
0
0
0
0
12
23
78
% R
% Ser:
0
45
0
0
0
0
0
78
0
12
0
0
0
67
0
% S
% Thr:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
12
12
0
0
12
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _