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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS7
All Species:
37.88
Human Site:
S427
Identified Species:
69.44
UniProt:
Q9NVH2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVH2
NP_056249.1
962
106834
S427
A
K
G
R
P
H
L
S
Q
S
V
V
E
T
L
Chimpanzee
Pan troglodytes
XP_514179
963
106947
S428
A
K
G
R
P
H
L
S
Q
S
V
V
E
T
L
Rhesus Macaque
Macaca mulatta
XP_001108251
962
106749
S427
A
K
G
R
P
H
L
S
Q
S
V
V
E
T
L
Dog
Lupus familis
XP_547398
962
106813
S427
A
K
G
R
P
H
L
S
Q
S
V
V
E
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQK1
966
106842
S427
A
K
G
R
P
H
L
S
R
S
V
V
D
T
L
Rat
Rattus norvegicus
XP_223075
967
106895
S427
A
K
G
R
P
H
L
S
R
S
V
V
D
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510160
962
106679
S427
A
K
C
R
P
H
L
S
Q
S
V
V
E
P
L
Chicken
Gallus gallus
Q5ZL91
961
106512
S426
V
K
C
R
P
H
L
S
Q
S
V
V
E
S
L
Frog
Xenopus laevis
NP_001090550
982
109149
S429
A
K
C
R
P
Y
L
S
Q
S
V
V
E
S
L
Zebra Danio
Brachydanio rerio
Q8JGR7
964
106897
S427
L
K
T
C
P
H
L
S
Q
S
S
V
E
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648352
1001
112270
L454
A
E
L
M
C
E
A
L
A
G
L
C
E
H
F
Honey Bee
Apis mellifera
XP_396796
958
105986
C418
C
R
A
Q
P
S
H
C
S
I
F
V
D
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789961
795
89051
L305
H
I
P
D
Q
V
D
L
L
L
G
Y
L
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
98.6
N.A.
94.9
95
N.A.
95.4
91.8
83.8
76.1
N.A.
35.6
40.5
N.A.
32.2
Protein Similarity:
100
99.9
99.6
99.1
N.A.
98.2
98.1
N.A.
97.7
95.1
91.8
87.8
N.A.
54.2
59.3
N.A.
47
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
80
80
66.6
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
93.3
66.6
N.A.
26.6
40
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
8
0
0
0
8
0
8
0
0
0
0
8
0
% A
% Cys:
8
0
24
8
8
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
24
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
0
0
0
0
70
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
0
47
0
0
0
0
0
0
8
8
0
0
0
0
% G
% His:
8
0
0
0
0
70
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
0
77
16
8
8
8
0
8
8
77
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
85
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
8
0
0
0
62
0
0
0
0
0
0
% Q
% Arg:
0
8
0
70
0
0
0
0
16
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
77
8
77
8
0
0
16
8
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
47
0
% T
% Val:
8
0
0
0
0
8
0
0
0
0
70
85
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _