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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS7 All Species: 39.39
Human Site: T857 Identified Species: 72.22
UniProt: Q9NVH2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVH2 NP_056249.1 962 106834 T857 V C L N V S S T L Q S K S G Q
Chimpanzee Pan troglodytes XP_514179 963 106947 T858 V C L N V S S T L Q S K S G Q
Rhesus Macaque Macaca mulatta XP_001108251 962 106749 T857 V C L N V S S T L Q S K S G Q
Dog Lupus familis XP_547398 962 106813 T857 V C L N V S S T L Q S K S G Q
Cat Felis silvestris
Mouse Mus musculus Q7TQK1 966 106842 T857 V C L N V S S T L Q S K S G Q
Rat Rattus norvegicus XP_223075 967 106895 T857 V C L N V S S T L Q S K S S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510160 962 106679 T857 V C L N V S S T L Q S K S G Q
Chicken Gallus gallus Q5ZL91 961 106512 V856 V C L N V S S V L Q S K S G Q
Frog Xenopus laevis NP_001090550 982 109149 T859 V C L N V S S T L Q T K P G Q
Zebra Danio Brachydanio rerio Q8JGR7 964 106897 T857 V C L K V S S T L Q T K P G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648352 1001 112270 T904 S L T S Q L I T P P P R S S Q
Honey Bee Apis mellifera XP_396796 958 105986 S855 V C I S I S T S P P S K I N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789961 795 89051 H699 R A G A T P N H P L K F Q T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.4 98.6 N.A. 94.9 95 N.A. 95.4 91.8 83.8 76.1 N.A. 35.6 40.5 N.A. 32.2
Protein Similarity: 100 99.9 99.6 99.1 N.A. 98.2 98.1 N.A. 97.7 95.1 91.8 87.8 N.A. 54.2 59.3 N.A. 47
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 100 93.3 86.6 73.3 N.A. 20 33.3 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 93.3 93.3 80 N.A. 33.3 66.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 85 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 70 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 8 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 8 85 0 0 0 % K
% Leu: 0 8 77 0 0 8 0 0 77 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 70 0 0 8 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 8 0 0 24 16 8 0 16 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 77 0 0 8 0 77 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 8 0 0 16 0 85 77 8 0 0 70 0 70 16 16 % S
% Thr: 0 0 8 0 8 0 8 77 0 0 16 0 0 8 0 % T
% Val: 85 0 0 0 77 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _