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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
15.15
Human Site:
S1186
Identified Species:
25.64
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S1186
Y
Y
L
Q
V
C
Q
S
S
G
G
I
P
K
N
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S1186
Y
Y
L
Q
V
C
Q
S
S
G
G
I
P
K
N
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
T1146
K
L
S
G
S
H
L
T
P
V
C
Y
S
F
I
Dog
Lupus familis
XP_545849
1234
138558
Y1112
S
H
L
T
P
L
C
Y
S
F
I
S
Y
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
S1187
Y
Y
L
Q
V
C
Q
S
S
R
G
I
P
N
T
Rat
Rattus norvegicus
XP_001064803
1332
149518
S1189
Y
Y
L
Q
V
C
Q
S
S
R
R
I
P
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
L614
V
K
L
S
G
S
H
L
T
P
Q
C
Y
A
F
Chicken
Gallus gallus
NP_001108323
1338
149271
G1189
S
T
S
N
T
V
P
G
R
L
E
K
L
V
K
Frog
Xenopus laevis
NP_001164682
1337
149488
Q1192
I
C
S
S
H
G
G
Q
I
S
A
R
L
E
K
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
T1182
Y
Y
I
Q
L
C
A
T
Q
P
G
Q
L
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
I584
E
G
L
Y
N
S
A
I
K
N
P
E
I
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
D867
Q
Q
A
D
H
V
L
D
D
T
E
W
L
V
V
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
M1217
F
Y
K
H
L
A
Q
M
S
R
L
R
I
A
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
L1257
V
E
L
T
C
K
S
L
T
V
P
L
Y
P
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
0
13.3
N.A.
80
73.3
N.A.
6.6
0
0
33.3
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
6.6
20
N.A.
80
73.3
N.A.
13.3
0
6.6
53.3
N.A.
N.A.
6.6
N.A.
0
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
15
0
0
0
8
0
0
15
8
% A
% Cys:
0
8
0
0
8
36
8
0
0
0
8
8
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
0
15
8
0
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
15
% F
% Gly:
0
8
0
8
8
8
8
8
0
15
29
0
0
0
0
% G
% His:
0
8
0
8
15
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
8
8
0
8
29
15
8
8
% I
% Lys:
8
8
8
0
0
8
0
0
8
0
0
8
0
15
15
% K
% Leu:
0
8
58
0
15
8
15
15
0
8
8
8
29
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
8
0
0
0
15
15
% N
% Pro:
0
0
0
0
8
0
8
0
8
15
15
0
29
15
0
% P
% Gln:
8
8
0
36
0
0
36
8
8
0
8
8
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
22
8
15
0
0
0
% R
% Ser:
15
0
22
15
8
15
8
29
43
8
0
8
8
0
8
% S
% Thr:
0
8
0
15
8
0
0
15
15
8
0
0
0
0
15
% T
% Val:
15
0
0
0
29
15
0
0
0
15
0
0
0
22
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
36
43
0
8
0
0
0
8
0
0
0
8
22
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _