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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
13.33
Human Site:
S1220
Identified Species:
22.56
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S1220
I
S
Y
V
Q
N
K
S
K
S
L
N
Y
T
G
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S1220
I
S
Y
V
Q
N
K
S
K
S
L
N
Y
T
G
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
M1180
P
A
T
V
A
T
A
M
A
R
V
L
R
E
T
Dog
Lupus familis
XP_545849
1234
138558
L1146
A
T
A
M
A
R
V
L
R
E
T
K
P
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
S1221
I
S
Y
V
Q
N
K
S
S
D
A
P
K
C
S
Rat
Rattus norvegicus
XP_001064803
1332
149518
S1223
I
S
Y
V
Q
N
K
S
S
N
N
P
K
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
A648
K
T
A
A
V
A
P
A
K
V
F
Q
K
A
K
Chicken
Gallus gallus
NP_001108323
1338
149271
F1223
I
H
S
E
S
L
S
F
A
E
E
K
K
K
K
Frog
Xenopus laevis
NP_001164682
1337
149488
S1226
V
Q
N
I
H
S
E
S
L
S
L
A
A
E
K
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
X1216
F
I
T
Y
V
Q
V
X
S
E
K
L
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
E618
I
L
P
P
V
K
L
E
L
C
T
D
I
H
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
T901
L
A
T
Q
R
E
D
T
E
K
A
I
C
N
Q
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
L1251
C
K
Q
L
T
V
P
L
Y
N
F
V
A
E
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
L1291
R
I
Q
K
R
E
V
L
L
L
F
Q
I
Q
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
6.6
0
N.A.
53.3
53.3
N.A.
6.6
6.6
20
0
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
20
20
N.A.
53.3
60
N.A.
20
6.6
46.6
0
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
15
8
15
8
8
8
15
0
15
8
15
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
8
15
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% D
% Glu:
0
0
0
8
0
15
8
8
8
22
8
0
0
22
8
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
22
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
43
15
0
8
0
0
0
0
0
0
0
8
15
8
0
% I
% Lys:
8
8
0
8
0
8
29
0
22
8
8
15
36
15
29
% K
% Leu:
8
8
0
8
0
8
8
22
22
8
22
15
0
0
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
29
0
0
0
15
8
15
0
8
0
% N
% Pro:
8
0
8
8
0
0
15
0
0
0
0
15
8
0
15
% P
% Gln:
0
8
15
8
29
8
0
0
0
0
0
15
0
8
8
% Q
% Arg:
8
0
0
0
15
8
0
0
8
8
0
0
8
0
0
% R
% Ser:
0
29
8
0
8
8
8
36
22
22
0
0
0
0
8
% S
% Thr:
0
15
22
0
8
8
0
8
0
0
15
0
0
15
8
% T
% Val:
8
0
0
36
22
8
22
0
0
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
29
8
0
0
0
0
8
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _