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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
20
Human Site:
S454
Identified Species:
33.85
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S454
R
V
V
T
R
A
S
S
P
I
S
H
F
L
D
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S454
R
V
V
T
R
A
S
S
P
I
S
H
F
L
D
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
L445
Q
E
I
L
E
Q
V
L
N
R
V
V
T
R
A
Dog
Lupus familis
XP_545849
1234
138558
I411
H
E
M
I
R
Q
E
I
L
E
Q
V
L
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
S453
N
R
V
V
T
R
T
S
S
P
I
N
H
F
L
Rat
Rattus norvegicus
XP_001064803
1332
149518
S453
N
R
V
V
T
R
T
S
S
P
I
S
H
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
Chicken
Gallus gallus
NP_001108323
1338
149271
S456
R
V
L
T
K
A
A
S
P
V
S
H
F
I
D
Frog
Xenopus laevis
NP_001164682
1337
149488
T455
R
V
I
T
K
A
A
T
P
V
T
H
F
I
D
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
S454
R
L
V
T
K
T
A
S
P
V
T
H
F
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
Q166
G
T
P
S
T
P
N
Q
Q
A
S
Q
L
G
R
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
E450
R
I
L
S
L
K
P
E
K
N
I
P
I
I
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
A451
R
I
L
S
L
K
C
A
K
S
K
P
I
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
0
6.6
N.A.
13.3
13.3
N.A.
0
66.6
53.3
53.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
26.6
20
N.A.
0
100
100
93.3
N.A.
N.A.
0
N.A.
20
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
29
22
8
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% D
% Glu:
0
15
0
0
8
0
8
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
36
15
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
36
15
0
0
% H
% Ile:
0
15
15
8
0
0
0
8
0
15
22
0
15
29
0
% I
% Lys:
0
0
0
0
22
15
0
0
15
0
8
0
0
0
0
% K
% Leu:
0
8
22
8
15
0
0
8
8
0
0
0
15
15
15
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
8
0
8
8
0
8
0
8
0
% N
% Pro:
0
0
8
0
0
8
8
0
36
15
0
15
0
0
0
% P
% Gln:
8
0
0
0
0
15
0
8
8
0
8
8
0
0
0
% Q
% Arg:
50
15
0
0
22
15
0
0
0
8
0
0
0
8
29
% R
% Ser:
0
0
0
22
0
0
15
43
15
8
29
8
0
0
0
% S
% Thr:
0
8
0
36
22
8
15
8
0
0
15
0
8
0
0
% T
% Val:
0
29
36
15
0
0
8
0
0
22
8
15
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _