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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCI
All Species:
7.88
Human Site:
S659
Identified Species:
13.33
UniProt:
Q9NVI1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVI1
NP_001106849.1
1328
149324
S659
L
T
Q
G
D
K
I
S
L
Q
E
P
L
D
Y
Chimpanzee
Pan troglodytes
XP_001166960
1328
149462
S659
L
T
Q
G
D
K
I
S
L
Q
E
P
L
D
Y
Rhesus Macaque
Macaca mulatta
XP_001092590
1268
142835
P637
Q
L
K
Q
F
Y
E
P
K
P
D
L
L
P
P
Dog
Lupus familis
XP_545849
1234
138558
K603
Q
T
L
L
S
Q
L
K
Q
F
Y
E
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K368
1330
149307
F658
L
T
Q
G
S
Q
I
F
L
Q
E
P
L
D
H
Rat
Rattus norvegicus
XP_001064803
1332
149518
F658
L
T
Q
G
S
Q
T
F
L
Q
E
P
L
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513065
736
82976
E105
Q
H
P
L
Q
H
E
E
D
E
E
G
G
L
Q
Chicken
Gallus gallus
NP_001108323
1338
149271
F661
M
A
Q
G
D
Q
I
F
L
Q
E
P
L
A
H
Frog
Xenopus laevis
NP_001164682
1337
149488
F660
T
A
Q
G
D
H
I
F
L
Q
E
P
L
A
H
Zebra Danio
Brachydanio rerio
XP_001921139
1367
152995
F659
S
A
Q
G
D
Q
V
F
L
Q
E
P
L
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122372
706
81709
R75
W
I
I
A
D
F
P
R
Y
S
K
Q
H
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190805
989
110178
R358
L
T
Q
Q
A
D
I
R
L
V
L
Y
E
G
L
Poplar Tree
Populus trichocarpa
XP_002315511
1406
157649
V651
K
S
L
S
G
N
V
V
I
E
E
P
L
D
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119400
1470
164337
T652
R
V
E
G
D
K
F
T
I
E
E
P
L
D
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93
81.4
N.A.
80.8
81.3
N.A.
39.7
66.9
66.9
59.4
N.A.
N.A.
20.4
N.A.
33.3
Protein Similarity:
100
99.6
94.2
86.5
N.A.
89.6
89.8
N.A.
46.9
81.6
81.5
75.9
N.A.
N.A.
33
N.A.
49.4
P-Site Identity:
100
100
6.6
6.6
N.A.
73.3
60
N.A.
6.6
60
60
53.3
N.A.
N.A.
6.6
N.A.
33.3
P-Site Similarity:
100
100
20
26.6
N.A.
86.6
73.3
N.A.
13.3
80
66.6
73.3
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
22.7
N.A.
N.A.
23.4
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
43
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
8
8
0
0
0
0
0
0
0
0
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
8
0
0
8
0
8
0
0
36
0
% D
% Glu:
0
0
8
0
0
0
15
8
0
22
72
8
8
8
0
% E
% Phe:
0
0
0
0
8
8
8
36
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
58
8
0
0
0
0
0
0
8
8
15
0
% G
% His:
0
8
0
0
0
15
0
0
0
0
0
0
8
0
36
% H
% Ile:
0
8
8
0
0
0
43
0
15
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
0
22
0
8
8
0
8
0
0
0
0
% K
% Leu:
36
8
15
15
0
0
8
0
58
0
8
8
72
15
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
8
8
0
8
0
65
8
8
15
% P
% Gln:
22
0
58
15
8
36
0
0
8
50
0
8
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
15
0
0
0
0
0
0
8
% R
% Ser:
8
8
0
8
22
0
0
15
0
8
0
0
0
0
0
% S
% Thr:
8
43
0
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
15
8
0
8
0
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
8
8
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _