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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FANCI All Species: 23.64
Human Site: S803 Identified Species: 40
UniProt: Q9NVI1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVI1 NP_001106849.1 1328 149324 S803 M A N K T S D S L L S M K F V
Chimpanzee Pan troglodytes XP_001166960 1328 149462 S803 T A N K T N D S L L S M K F V
Rhesus Macaque Macaca mulatta XP_001092590 1268 142835 I771 S K N K F E D I L S L F M C Y
Dog Lupus familis XP_545849 1234 138558 E737 N F S K N K F E E V L S L F M
Cat Felis silvestris
Mouse Mus musculus Q8K368 1330 149307 S802 M T S K V S D S L L S L K F V
Rat Rattus norvegicus XP_001064803 1332 149518 S804 M A S K A S D S L L S M K F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513065 736 82976 E239 R D N A Q S H E E S L A V L R
Chicken Gallus gallus NP_001108323 1338 149271 S806 L G N R I A R S F L S M G F V
Frog Xenopus laevis NP_001164682 1337 149488 S806 G N N K T A R S L I S M T F V
Zebra Danio Brachydanio rerio XP_001921139 1367 152995 S804 A S S K T P R S L L S L G F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122372 706 81709 S209 Q K L L S A L S K Y F N L Y Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190805 989 110178 S492 E D F H V D K S A D F S T T S
Poplar Tree Populus trichocarpa XP_002315511 1406 157649 K800 T R L S T G I K R G N V R A T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001119400 1470 164337 V803 G K S K Q S N V G K R V R F S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93 81.4 N.A. 80.8 81.3 N.A. 39.7 66.9 66.9 59.4 N.A. N.A. 20.4 N.A. 33.3
Protein Similarity: 100 99.6 94.2 86.5 N.A. 89.6 89.8 N.A. 46.9 81.6 81.5 75.9 N.A. N.A. 33 N.A. 49.4
P-Site Identity: 100 86.6 26.6 13.3 N.A. 73.3 86.6 N.A. 13.3 46.6 60 53.3 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 93.3 26.6 33.3 N.A. 86.6 93.3 N.A. 13.3 66.6 73.3 73.3 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: 22.7 N.A. N.A. 23.4 N.A. N.A.
Protein Similarity: 44.1 N.A. N.A. 43 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 0 8 8 22 0 0 8 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 15 0 0 0 8 36 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 8 0 15 15 0 0 0 0 0 0 % E
% Phe: 0 8 8 0 8 0 8 0 8 0 15 8 0 65 0 % F
% Gly: 15 8 0 0 0 8 0 0 8 8 0 0 15 0 0 % G
% His: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 8 8 0 8 0 0 0 0 0 % I
% Lys: 0 22 0 65 0 8 8 8 8 8 0 0 29 0 0 % K
% Leu: 8 0 15 8 0 0 8 0 50 43 22 15 15 8 0 % L
% Met: 22 0 0 0 0 0 0 0 0 0 0 36 8 0 8 % M
% Asn: 8 8 43 0 8 8 8 0 0 0 8 8 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 8 0 0 22 0 8 0 8 0 15 0 8 % R
% Ser: 8 8 36 8 8 36 0 65 0 15 50 15 0 0 15 % S
% Thr: 15 8 0 0 36 0 0 0 0 0 0 0 15 8 8 % T
% Val: 0 0 0 0 15 0 0 8 0 8 0 15 8 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _