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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR1OP2 All Species: 20.61
Human Site: S131 Identified Species: 41.21
UniProt: Q9NVK5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVK5 NP_056448.1 253 29426 S131 M K L K E Q H S K I D M V H R
Chimpanzee Pan troglodytes XP_001143861 215 24959 S131 M K L K E Q H S K E L Q A H V
Rhesus Macaque Macaca mulatta XP_001111696 207 23730 D123 M V A K K A V D A E P V L K A
Dog Lupus familis XP_543752 253 29375 S131 T K L K E Q H S K I D M V H R
Cat Felis silvestris
Mouse Mus musculus Q9CRA9 253 29356 S131 M K L K E Q H S K I D M V H R
Rat Rattus norvegicus Q5FWT9 207 23559 D123 M V A K Q A V D A E P V L K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512915 123 14383 Q44 I V M K L K E Q H S K I H T V
Chicken Gallus gallus Q5ZKJ4 217 25179 S133 M K L K E Q H S K E L Q V H V
Frog Xenopus laevis Q8AVR2 215 25268 S131 M K L K E Q H S K E L Q A H I
Zebra Danio Brachydanio rerio Q7T338 215 24988 T131 T Q L R E Q H T N E M Q A H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM65 315 35131 E176 L E N E T L R E L L Q I S K Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786805 249 28580 V149 K I I E M A A V M Q R A I N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.9 43.8 97.6 N.A. 98.8 43.8 N.A. 40.7 79.4 69.5 66 N.A. 22.5 N.A. N.A. 35.1
Protein Similarity: 100 84.9 60.8 98 N.A. 99.2 61.6 N.A. 43 83 77.4 77.8 N.A. 47.9 N.A. N.A. 55.3
P-Site Identity: 100 66.6 13.3 93.3 N.A. 100 13.3 N.A. 6.6 73.3 66.6 33.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 66.6 33.3 93.3 N.A. 100 33.3 N.A. 33.3 73.3 66.6 53.3 N.A. 40 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 25 9 0 17 0 0 9 25 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 17 0 0 25 0 0 0 0 % D
% Glu: 0 9 0 17 59 0 9 9 0 50 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 59 0 9 0 0 0 9 59 0 % H
% Ile: 9 9 9 0 0 0 0 0 0 25 0 17 9 0 17 % I
% Lys: 9 50 0 75 9 9 0 0 50 0 9 0 0 25 0 % K
% Leu: 9 0 59 0 9 9 0 0 9 9 25 0 17 0 0 % L
% Met: 59 0 9 0 9 0 0 0 9 0 9 25 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 9 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % P
% Gln: 0 9 0 0 9 59 0 9 0 9 9 34 0 0 9 % Q
% Arg: 0 0 0 9 0 0 9 0 0 0 9 0 0 0 25 % R
% Ser: 0 0 0 0 0 0 0 50 0 9 0 0 9 0 0 % S
% Thr: 17 0 0 0 9 0 0 9 0 0 0 0 0 9 0 % T
% Val: 0 25 0 0 0 0 17 9 0 0 0 17 34 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _