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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR1OP2
All Species:
12.12
Human Site:
S149
Identified Species:
24.24
UniProt:
Q9NVK5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVK5
NP_056448.1
253
29426
S149
E
G
F
F
L
D
A
S
R
H
I
L
E
A
P
Chimpanzee
Pan troglodytes
XP_001143861
215
24959
R149
T
E
M
A
A
V
M
R
K
A
I
E
I
D
E
Rhesus Macaque
Macaca mulatta
XP_001111696
207
23730
Q141
H
S
A
E
I
E
S
Q
I
D
R
I
C
E
M
Dog
Lupus familis
XP_543752
253
29375
S149
E
G
F
F
L
D
A
S
R
H
I
F
E
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRA9
253
29356
S149
E
G
F
F
L
D
A
S
R
H
I
L
E
A
P
Rat
Rattus norvegicus
Q5FWT9
207
23559
Q141
H
S
A
E
I
E
S
Q
I
D
R
I
C
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512915
123
14383
D62
R
S
E
G
L
L
L
D
A
S
R
R
I
L
E
Chicken
Gallus gallus
Q5ZKJ4
217
25179
R151
T
E
M
A
A
V
M
R
K
A
I
E
I
D
D
Frog
Xenopus laevis
Q8AVR2
215
25268
R149
N
E
M
T
A
V
M
R
R
A
I
E
M
D
E
Zebra Danio
Brachydanio rerio
Q7T338
215
24988
R149
N
E
M
A
T
V
M
R
K
A
I
E
V
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM65
315
35131
S194
S
Q
R
P
I
R
E
S
D
H
L
L
E
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786805
249
28580
T167
T
S
Y
D
V
E
E
T
L
A
R
L
Q
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
43.8
97.6
N.A.
98.8
43.8
N.A.
40.7
79.4
69.5
66
N.A.
22.5
N.A.
N.A.
35.1
Protein Similarity:
100
84.9
60.8
98
N.A.
99.2
61.6
N.A.
43
83
77.4
77.8
N.A.
47.9
N.A.
N.A.
55.3
P-Site Identity:
100
6.6
0
86.6
N.A.
100
0
N.A.
6.6
6.6
13.3
6.6
N.A.
26.6
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
26.6
86.6
N.A.
100
26.6
N.A.
6.6
13.3
13.3
13.3
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
25
25
0
25
0
9
42
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% C
% Asp:
0
0
0
9
0
25
0
9
9
17
0
0
0
34
9
% D
% Glu:
25
34
9
17
0
25
17
0
0
0
0
34
34
25
42
% E
% Phe:
0
0
25
25
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
25
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
17
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% H
% Ile:
0
0
0
0
25
0
0
0
17
0
59
17
25
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
34
9
9
0
9
0
9
34
0
9
0
% L
% Met:
0
0
34
0
0
0
34
0
0
0
0
0
9
9
17
% M
% Asn:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
9
0
0
0
0
0
17
0
0
0
0
9
0
0
% Q
% Arg:
9
0
9
0
0
9
0
34
34
0
34
9
0
0
0
% R
% Ser:
9
34
0
0
0
0
17
34
0
9
0
0
0
0
9
% S
% Thr:
25
0
0
9
9
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
34
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _