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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR1OP2
All Species:
25.15
Human Site:
S224
Identified Species:
50.3
UniProt:
Q9NVK5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVK5
NP_056448.1
253
29426
S224
I
L
Q
I
T
R
E
S
F
L
N
L
R
K
D
Chimpanzee
Pan troglodytes
XP_001143861
215
24959
S186
I
L
Q
I
T
R
E
S
F
L
N
L
R
K
D
Rhesus Macaque
Macaca mulatta
XP_001111696
207
23730
E176
K
L
A
Q
L
E
L
E
N
K
E
L
R
E
L
Dog
Lupus familis
XP_543752
253
29375
S224
I
L
Q
I
T
R
E
S
F
L
N
L
R
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRA9
253
29356
S224
I
L
Q
I
T
R
E
S
F
L
N
L
R
K
D
Rat
Rattus norvegicus
Q5FWT9
207
23559
E176
K
L
A
Q
L
E
L
E
N
K
E
L
R
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512915
123
14383
S95
Q
V
H
V
D
Q
I
S
E
M
A
A
V
M
R
Chicken
Gallus gallus
Q5ZKJ4
217
25179
S188
I
L
Q
I
T
R
E
S
F
L
N
L
K
K
E
Frog
Xenopus laevis
Q8AVR2
215
25268
S186
I
L
Q
I
T
K
I
S
F
L
N
L
H
K
E
Zebra Danio
Brachydanio rerio
Q7T338
215
24988
A186
L
L
G
I
S
R
E
A
F
L
L
L
K
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM65
315
35131
T271
A
P
S
V
T
L
E
T
A
P
P
G
E
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786805
249
28580
D214
R
E
K
G
R
D
D
D
A
E
K
D
N
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
43.8
97.6
N.A.
98.8
43.8
N.A.
40.7
79.4
69.5
66
N.A.
22.5
N.A.
N.A.
35.1
Protein Similarity:
100
84.9
60.8
98
N.A.
99.2
61.6
N.A.
43
83
77.4
77.8
N.A.
47.9
N.A.
N.A.
55.3
P-Site Identity:
100
100
20
100
N.A.
100
20
N.A.
6.6
86.6
73.3
53.3
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
26.6
N.A.
33.3
100
86.6
86.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
0
0
0
9
17
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
9
9
0
0
0
9
0
0
42
% D
% Glu:
0
9
0
0
0
17
59
17
9
9
17
0
9
34
17
% E
% Phe:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
50
0
0
59
0
0
17
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
9
0
0
9
0
0
0
17
9
0
17
50
0
% K
% Leu:
9
75
0
0
17
9
17
0
0
59
9
75
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
17
0
50
0
9
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
9
% P
% Gln:
9
0
50
17
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
9
50
0
0
0
0
0
0
50
9
9
% R
% Ser:
0
0
9
0
9
0
0
59
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
59
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
9
0
17
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _