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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR1OP2 All Species: 24.68
Human Site: S249 Identified Species: 49.35
UniProt: Q9NVK5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVK5 NP_056448.1 253 29426 S249 L V T N S D L S L R K S _ _ _
Chimpanzee Pan troglodytes XP_001143861 215 24959 S211 L V T N S D L S L R K S _ _ _
Rhesus Macaque Macaca mulatta XP_001111696 207 23730 T201 R K E N S M D T A S Q A I K _
Dog Lupus familis XP_543752 253 29375 S249 L V T N S D L S L R K S _ _ _
Cat Felis silvestris
Mouse Mus musculus Q9CRA9 253 29356 S249 L V T N S D L S L R K S _ _ _
Rat Rattus norvegicus Q5FWT9 207 23559 P201 G K E S S V A P E A Q T I R _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512915 123 14383
Chicken Gallus gallus Q5ZKJ4 217 25179 S213 L V T S S D L S L R K S _ _ _
Frog Xenopus laevis Q8AVR2 215 25268 I211 P V P N T D L I L R K S _ _ _
Zebra Danio Brachydanio rerio Q7T338 215 24988 S211 L L T S T D I S L R K S _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM65 315 35131 P296 V N T T S A P P P A T T S N E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786805 249 28580 I239 V I H D T T I I Q K D K N G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.9 43.8 97.6 N.A. 98.8 43.8 N.A. 40.7 79.4 69.5 66 N.A. 22.5 N.A. N.A. 35.1
Protein Similarity: 100 84.9 60.8 98 N.A. 99.2 61.6 N.A. 43 83 77.4 77.8 N.A. 47.9 N.A. N.A. 55.3
P-Site Identity: 100 100 14.2 100 N.A. 100 7.1 N.A. 0 91.6 66.6 66.6 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 42.8 100 N.A. 100 35.7 N.A. 0 100 75 100 N.A. 26.6 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 9 0 9 17 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 59 9 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 17 0 0 0 0 0 9 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 17 17 0 0 0 0 17 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 9 59 9 0 9 0 % K
% Leu: 50 9 0 0 0 0 50 0 59 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 50 0 0 0 0 0 0 0 0 9 9 0 % N
% Pro: 9 0 9 0 0 0 9 17 9 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 17 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 59 0 0 0 9 0 % R
% Ser: 0 0 0 25 67 0 0 50 0 9 0 59 9 0 0 % S
% Thr: 0 0 59 9 25 9 0 9 0 0 9 17 0 0 0 % T
% Val: 17 50 0 0 0 9 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 59 59 75 % _