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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR1OP2 All Species: 35.15
Human Site: Y46 Identified Species: 70.3
UniProt: Q9NVK5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVK5 NP_056448.1 253 29426 Y46 R V E A M K Q Y Q E E I Q E L
Chimpanzee Pan troglodytes XP_001143861 215 24959 Y46 R V E A M K Q Y Q E E I Q E L
Rhesus Macaque Macaca mulatta XP_001111696 207 23730 A46 R V A A M R E A G T A L P D Q
Dog Lupus familis XP_543752 253 29375 Y46 R V E A M K Q Y Q E E I Q E L
Cat Felis silvestris
Mouse Mus musculus Q9CRA9 253 29356 Y46 R V E A M K Q Y Q E E I Q E L
Rat Rattus norvegicus Q5FWT9 207 23559 A46 R V A A M R E A G A V L P E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512915 123 14383
Chicken Gallus gallus Q5ZKJ4 217 25179 Y48 R V E A M K Q Y Q E E I Q E L
Frog Xenopus laevis Q8AVR2 215 25268 Y46 R V E A M K Q Y Q E E V Q E L
Zebra Danio Brachydanio rerio Q7T338 215 24988 Y46 R V E A M K Q Y Q E E I E V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM65 315 35131 Y47 L V E S L R Q Y Q D D I E S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786805 249 28580 Y46 K I E V M K E Y Q E E I E E M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.9 43.8 97.6 N.A. 98.8 43.8 N.A. 40.7 79.4 69.5 66 N.A. 22.5 N.A. N.A. 35.1
Protein Similarity: 100 84.9 60.8 98 N.A. 99.2 61.6 N.A. 43 83 77.4 77.8 N.A. 47.9 N.A. N.A. 55.3
P-Site Identity: 100 100 26.6 100 N.A. 100 33.3 N.A. 0 100 93.3 86.6 N.A. 46.6 N.A. N.A. 60
P-Site Similarity: 100 100 53.3 100 N.A. 100 53.3 N.A. 0 100 100 93.3 N.A. 86.6 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 75 0 0 0 17 0 9 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 9 0 0 9 0 % D
% Glu: 0 0 75 0 0 0 25 0 0 67 67 0 25 67 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 67 0 0 0 % I
% Lys: 9 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 9 0 0 0 0 0 0 17 0 0 67 % L
% Met: 0 0 0 0 84 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % P
% Gln: 0 0 0 0 0 0 67 0 75 0 0 0 50 0 17 % Q
% Arg: 75 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % T
% Val: 0 84 0 9 0 0 0 0 0 0 9 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _