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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT7 All Species: 42.73
Human Site: S224 Identified Species: 67.14
UniProt: Q9NVM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVM4 NP_061896.1 692 78459 S224 E S C P G A P S V C D I Q L N
Chimpanzee Pan troglodytes XP_511055 649 73905 S224 E S C P G A P S V C D I Q L N
Rhesus Macaque Macaca mulatta XP_001099228 701 79288 S224 E N C P G A P S V C D I Q L N
Dog Lupus familis XP_536808 691 78200 S224 E R C P G A P S V Y D I Q L N
Cat Felis silvestris
Mouse Mus musculus Q922X9 692 78283 S224 E R C P G A P S V C D I Q L N
Rat Rattus norvegicus Q5U4E8 693 78328 S224 E R C P G A P S V Y D I Q L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505676 689 78245 S224 E N C P G A P S V Y D I Q L N
Chicken Gallus gallus Q5ZIB9 689 78053 S224 E N C P G V P S V C D I Q L N
Frog Xenopus laevis Q6PCI6 685 77273 S220 E T C P G A P S V C D I Q L S
Zebra Danio Brachydanio rerio A2AV36 683 76528 S220 Q E C A G A P S V C D I Q L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V1 690 77927 A220 K S C Q G E A A L H D V Q L S
Honey Bee Apis mellifera XP_392453 690 78204 D224 S G A A A V H D I Q L T Q F P
Nematode Worm Caenorhab. elegans Q9XW42 630 71248 D215 S G T A A V F D V Q L S E M K
Sea Urchin Strong. purpuratus XP_780353 686 76862 S223 T S C S G A A S V H D I Q L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944R7 724 80852 S261 E S L F G I K S Q Q Y S M H V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 93.5 87.5 N.A. 85.1 83.9 N.A. 74.8 68.3 64 62.2 N.A. 37.1 41 31 45.8
Protein Similarity: 100 92.6 96 93.5 N.A. 92.7 92.2 N.A. 84.8 82.3 77.8 76 N.A. 57.5 59.8 45.3 66.1
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 86.6 N.A. 86.6 86.6 86.6 73.3 N.A. 40 6.6 6.6 66.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 86.6 N.A. 93.3 93.3 100 86.6 N.A. 73.3 13.3 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. 29.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 20 14 67 14 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 80 0 0 0 0 0 0 47 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 14 0 0 80 0 0 0 0 % D
% Glu: 67 7 0 0 0 7 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 7 0 0 7 0 0 0 0 0 0 7 0 % F
% Gly: 0 14 0 0 87 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 14 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 7 0 0 7 0 0 74 0 0 0 % I
% Lys: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % K
% Leu: 0 0 7 0 0 0 0 0 7 0 14 0 0 80 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % M
% Asn: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 54 % N
% Pro: 0 0 0 60 0 0 67 0 0 0 0 0 0 0 7 % P
% Gln: 7 0 0 7 0 0 0 0 7 20 0 0 87 0 0 % Q
% Arg: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 14 34 0 7 0 0 0 80 0 0 0 14 0 0 27 % S
% Thr: 7 7 7 0 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 0 0 0 0 0 20 0 0 80 0 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 20 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _