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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT7
All Species:
22.73
Human Site:
S259
Identified Species:
35.71
UniProt:
Q9NVM4
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVM4
NP_061896.1
692
78459
S259
F
S
K
Q
V
S
S
S
A
A
C
H
S
R
R
Chimpanzee
Pan troglodytes
XP_511055
649
73905
S259
F
S
K
Q
V
S
S
S
A
A
C
H
S
R
R
Rhesus Macaque
Macaca mulatta
XP_001099228
701
79288
S259
F
S
K
Q
V
S
S
S
A
A
C
H
S
R
Q
Dog
Lupus familis
XP_536808
691
78200
S259
F
S
K
Q
V
S
S
S
A
A
C
H
S
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q922X9
692
78283
S259
F
S
K
Q
V
S
S
S
A
A
C
H
S
R
Q
Rat
Rattus norvegicus
Q5U4E8
693
78328
S259
F
S
K
Q
V
S
S
S
A
A
C
H
S
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505676
689
78245
K259
F
S
K
Q
V
H
S
K
P
A
C
H
V
I
Q
Chicken
Gallus gallus
Q5ZIB9
689
78053
A259
F
S
K
P
V
R
S
A
S
T
C
Y
R
A
Q
Frog
Xenopus laevis
Q6PCI6
685
77273
A255
F
S
C
Q
V
S
S
A
P
T
S
H
P
V
H
Zebra Danio
Brachydanio rerio
A2AV36
683
76528
A255
F
S
K
P
V
S
S
A
A
Q
S
Y
T
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1V1
690
77927
E255
F
Q
R
K
Q
E
R
E
K
Q
R
S
Q
L
L
Honey Bee
Apis mellifera
XP_392453
690
78204
E259
K
S
T
L
L
Y
N
E
K
R
C
L
H
V
K
Nematode Worm
Caenorhab. elegans
Q9XW42
630
71248
E250
E
E
K
I
I
F
D
E
S
F
V
R
E
A
V
Sea Urchin
Strong. purpuratus
XP_780353
686
76862
E258
F
T
K
G
D
F
T
E
N
R
T
R
N
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944R7
724
80852
N296
F
W
K
R
P
E
S
N
G
E
L
D
V
H
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.6
93.5
87.5
N.A.
85.1
83.9
N.A.
74.8
68.3
64
62.2
N.A.
37.1
41
31
45.8
Protein Similarity:
100
92.6
96
93.5
N.A.
92.7
92.2
N.A.
84.8
82.3
77.8
76
N.A.
57.5
59.8
45.3
66.1
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
60
40
46.6
53.3
N.A.
6.6
13.3
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
66.6
66.6
53.3
73.3
N.A.
20
33.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
47
47
0
0
0
14
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
60
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
7
0
0
0
0
7
0
0
0
% D
% Glu:
7
7
0
0
0
14
0
27
0
7
0
0
7
0
0
% E
% Phe:
87
0
0
0
0
14
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
54
7
7
7
% H
% Ile:
0
0
0
7
7
0
0
0
0
0
0
0
0
7
7
% I
% Lys:
7
0
80
7
0
0
0
7
14
0
0
0
0
7
7
% K
% Leu:
0
0
0
7
7
0
0
0
0
0
7
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
7
0
0
0
7
0
0
% N
% Pro:
0
0
0
14
7
0
0
0
14
0
0
0
7
0
0
% P
% Gln:
0
7
0
54
7
0
0
0
0
14
0
0
7
0
40
% Q
% Arg:
0
0
7
7
0
7
7
0
0
14
7
14
7
34
20
% R
% Ser:
0
74
0
0
0
54
74
40
14
0
14
7
40
0
7
% S
% Thr:
0
7
7
0
0
0
7
0
0
14
7
0
7
0
0
% T
% Val:
0
0
0
0
67
0
0
0
0
0
7
0
14
27
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _