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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT7 All Species: 35.76
Human Site: S272 Identified Species: 56.19
UniProt: Q9NVM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVM4 NP_061896.1 692 78459 S272 R R F E P L T S G R A Q V V L
Chimpanzee Pan troglodytes XP_511055 649 73905 S272 R R F E P L T S G R A Q V V L
Rhesus Macaque Macaca mulatta XP_001099228 701 79288 S272 R Q F E P L T S G R A Q V V L
Dog Lupus familis XP_536808 691 78200 S272 R Q F E P L A S G R A Q V V L
Cat Felis silvestris
Mouse Mus musculus Q922X9 692 78283 S272 R Q F V P L A S G Q A Q V V L
Rat Rattus norvegicus Q5U4E8 693 78328 S272 K Q F V P L A S G Q A Q V V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505676 689 78245 S272 I Q F E S V G S G K A Q V V L
Chicken Gallus gallus Q5ZIB9 689 78053 S272 A Q L D P V K S G K A Q I V L
Frog Xenopus laevis Q6PCI6 685 77273 S268 V H F T S L A S G A A Q V V L
Zebra Danio Brachydanio rerio A2AV36 683 76528 G268 V R F K S Q T G G R A Q V V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V1 690 77927 Q268 L L K L Q S K Q P G A A E L V
Honey Bee Apis mellifera XP_392453 690 78204 T272 V K P I I N G T A H A I F M W
Nematode Worm Caenorhab. elegans Q9XW42 630 71248 T263 A V A H S S G T I D A L L M W
Sea Urchin Strong. purpuratus XP_780353 686 76862 T271 V S C E S L I T G K C Q G V F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944R7 724 80852 G309 H I E A K T T G S V H A I I S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 93.5 87.5 N.A. 85.1 83.9 N.A. 74.8 68.3 64 62.2 N.A. 37.1 41 31 45.8
Protein Similarity: 100 92.6 96 93.5 N.A. 92.7 92.2 N.A. 84.8 82.3 77.8 76 N.A. 57.5 59.8 45.3 66.1
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 66.6 N.A. 60 46.6 60 66.6 N.A. 6.6 6.6 6.6 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 80 80 60 73.3 N.A. 20 26.6 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 29.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 7 0 0 27 0 7 7 87 14 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 7 40 0 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 60 0 0 0 0 0 0 0 0 0 7 0 7 % F
% Gly: 0 0 0 0 0 0 20 14 74 7 0 0 7 0 0 % G
% His: 7 7 0 7 0 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 7 7 0 7 7 0 7 0 7 0 0 7 14 7 0 % I
% Lys: 7 7 7 7 7 0 14 0 0 20 0 0 0 0 0 % K
% Leu: 7 7 7 7 0 54 0 0 0 0 0 7 7 7 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 0 47 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 0 40 0 0 7 7 0 7 0 14 0 74 0 0 0 % Q
% Arg: 34 20 0 0 0 0 0 0 0 34 0 0 0 0 0 % R
% Ser: 0 7 0 0 34 14 0 60 7 0 0 0 0 0 7 % S
% Thr: 0 0 0 7 0 7 34 20 0 0 0 0 0 0 0 % T
% Val: 27 7 0 14 0 14 0 0 0 7 0 0 60 74 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _