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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT7 All Species: 39.39
Human Site: S484 Identified Species: 61.9
UniProt: Q9NVM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVM4 NP_061896.1 692 78459 S484 G E P F F T T S L L P W H N L
Chimpanzee Pan troglodytes XP_511055 649 73905 E460 N I I E K R P E L L T N E D L
Rhesus Macaque Macaca mulatta XP_001099228 701 79288 S484 G E P F F T T S L L P W H S L
Dog Lupus familis XP_536808 691 78200 S484 G E P F F T T S L L P W H N L
Cat Felis silvestris
Mouse Mus musculus Q922X9 692 78283 S484 G E P F F T T S L L P W H N L
Rat Rattus norvegicus Q5U4E8 693 78328 S484 G E P F F T T S L L P W H N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505676 689 78245 S485 A E P F F T T S L L P W H N L
Chicken Gallus gallus Q5ZIB9 689 78053 S485 G E P F F T T S L L P W H N L
Frog Xenopus laevis Q6PCI6 685 77273 N479 G E P F F T T N L L P W H N L
Zebra Danio Brachydanio rerio A2AV36 683 76528 S479 G E P Y F S T S L L P W H S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V1 690 77927 A489 A E P Y F L N A I L P W D N F
Honey Bee Apis mellifera XP_392453 690 78204 S489 G E P Y F I T S I V P W E N L
Nematode Worm Caenorhab. elegans Q9XW42 630 71248 H442 S A M N P W N H L R F L Y D V
Sea Urchin Strong. purpuratus XP_780353 686 76862 T481 A E P F F I T T L L P W H N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944R7 724 80852 N527 P Y Y S G L E N G L P W Q N L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 93.5 87.5 N.A. 85.1 83.9 N.A. 74.8 68.3 64 62.2 N.A. 37.1 41 31 45.8
Protein Similarity: 100 92.6 96 93.5 N.A. 92.7 92.2 N.A. 84.8 82.3 77.8 76 N.A. 57.5 59.8 45.3 66.1
P-Site Identity: 100 20 93.3 100 N.A. 100 100 N.A. 93.3 100 93.3 80 N.A. 46.6 66.6 6.6 80
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 93.3 100 100 100 N.A. 66.6 86.6 26.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. 29.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 7 14 0 % D
% Glu: 0 80 0 7 0 0 7 7 0 0 0 0 14 0 0 % E
% Phe: 0 0 0 60 80 0 0 0 0 0 7 0 0 0 7 % F
% Gly: 60 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 67 0 0 % H
% Ile: 0 7 7 0 0 14 0 0 14 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 14 0 0 80 87 0 7 0 0 87 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 7 0 0 14 14 0 0 0 7 0 74 0 % N
% Pro: 7 0 80 0 7 0 7 0 0 0 87 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % R
% Ser: 7 0 0 7 0 7 0 60 0 0 0 0 0 14 0 % S
% Thr: 0 0 0 0 0 54 74 7 0 0 7 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 87 0 0 0 % W
% Tyr: 0 7 7 20 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _