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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT7 All Species: 27.27
Human Site: S608 Identified Species: 42.86
UniProt: Q9NVM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVM4 NP_061896.1 692 78459 S608 E L R R P G Q S H A A V L W M
Chimpanzee Pan troglodytes XP_511055 649 73905 S573 L W E Y P C R S L S E P W Q I
Rhesus Macaque Macaca mulatta XP_001099228 701 79288 S608 E L R R P G R S H A A V L W M
Dog Lupus familis XP_536808 691 78200 S608 N L R R P G R S H G A V L W M
Cat Felis silvestris
Mouse Mus musculus Q922X9 692 78283 S608 E L T R P G K S H G A V L W M
Rat Rattus norvegicus Q5U4E8 693 78328 S608 E L R R P G K S H G A V L W M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505676 689 78245 S609 T L L K P G K S H G A V L W M
Chicken Gallus gallus Q5ZIB9 689 78053 S609 N L L R K G K S H G A V L W M
Frog Xenopus laevis Q6PCI6 685 77273 C603 N L V R S G Q C H G A V L W M
Zebra Danio Brachydanio rerio A2AV36 683 76528 C603 P F T G R G R C H G V A L W M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V1 690 77927 C610 E L K H P R I C N G V A L W V
Honey Bee Apis mellifera XP_392453 690 78204 C609 P I L T N G M C N G V A L W I
Nematode Worm Caenorhab. elegans Q9XW42 630 71248 S555 N I D N M S S S N A I P M W M
Sea Urchin Strong. purpuratus XP_780353 686 76862 C604 D F S S R G T C H G I A L W M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944R7 724 80852 G641 P I T G P C S G E V Q I E F I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 93.5 87.5 N.A. 85.1 83.9 N.A. 74.8 68.3 64 62.2 N.A. 37.1 41 31 45.8
Protein Similarity: 100 92.6 96 93.5 N.A. 92.7 92.2 N.A. 84.8 82.3 77.8 76 N.A. 57.5 59.8 45.3 66.1
P-Site Identity: 100 13.3 93.3 80 N.A. 80 86.6 N.A. 66.6 66.6 66.6 33.3 N.A. 33.3 20 26.6 33.3
P-Site Similarity: 100 33.3 100 86.6 N.A. 86.6 93.3 N.A. 80 73.3 66.6 40 N.A. 53.3 40 46.6 40
Percent
Protein Identity: N.A. N.A. N.A. 29.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 20 54 27 0 0 0 % A
% Cys: 0 0 0 0 0 14 0 34 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 34 0 7 0 0 0 0 0 7 0 7 0 7 0 0 % E
% Phe: 0 14 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 14 0 74 0 7 0 67 0 0 0 0 0 % G
% His: 0 0 0 7 0 0 0 0 67 0 0 0 0 0 0 % H
% Ile: 0 20 0 0 0 0 7 0 0 0 14 7 0 0 20 % I
% Lys: 0 0 7 7 7 0 27 0 0 0 0 0 0 0 0 % K
% Leu: 7 60 20 0 0 0 0 0 7 0 0 0 80 0 0 % L
% Met: 0 0 0 0 7 0 7 0 0 0 0 0 7 0 74 % M
% Asn: 27 0 0 7 7 0 0 0 20 0 0 0 0 0 0 % N
% Pro: 20 0 0 0 60 0 0 0 0 0 0 14 0 0 0 % P
% Gln: 0 0 0 0 0 0 14 0 0 0 7 0 0 7 0 % Q
% Arg: 0 0 27 47 14 7 27 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 7 7 7 14 60 0 7 0 0 0 0 0 % S
% Thr: 7 0 20 7 0 0 7 0 0 0 0 0 0 0 0 % T
% Val: 0 0 7 0 0 0 0 0 0 7 20 54 0 0 7 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 7 87 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _