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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT7 All Species: 9.7
Human Site: S653 Identified Species: 15.24
UniProt: Q9NVM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVM4 NP_061896.1 692 78459 S653 K Q A V Y F F S P A P D P R A
Chimpanzee Pan troglodytes XP_511055 649 73905 Q610 R S S P F T F Q P C P R S Q S
Rhesus Macaque Macaca mulatta XP_001099228 701 79288 S653 K Q A V Y F F S P V L D P R A
Dog Lupus familis XP_536808 691 78200 F653 C K Q A V Y F F T T P D C R A
Cat Felis silvestris
Mouse Mus musculus Q922X9 692 78283 S653 K Q A V Y F L S T T L D L R V
Rat Rattus norvegicus Q5U4E8 693 78328 S653 K Q A V Y F L S A T L D P S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505676 689 78245 A649 W N T H C K Q A V Y F F S S I
Chicken Gallus gallus Q5ZIB9 689 78053 Q648 E W N P H C K Q A V Y F F S S
Frog Xenopus laevis Q6PCI6 685 77273 Q642 Q W Y P H R K Q G V Y F F S S
Zebra Danio Brachydanio rerio A2AV36 683 76528 Q642 E W N P H R K Q G V F F F R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V1 690 77927 M649 G E F V K W D M F V R Q G V H
Honey Bee Apis mellifera XP_392453 690 78204 V650 D P F T R Q G V H L F K D I T
Nematode Worm Caenorhab. elegans Q9XW42 630 71248 Q592 E W N K G Y K Q G V Y F P I T
Sea Urchin Strong. purpuratus XP_780353 686 76862 V647 D M H S K Q G V H F I K S N P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944R7 724 80852 K686 K Y W K Q G V K L L G K P V T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 93.5 87.5 N.A. 85.1 83.9 N.A. 74.8 68.3 64 62.2 N.A. 37.1 41 31 45.8
Protein Similarity: 100 92.6 96 93.5 N.A. 92.7 92.2 N.A. 84.8 82.3 77.8 76 N.A. 57.5 59.8 45.3 66.1
P-Site Identity: 100 20 86.6 33.3 N.A. 60 66.6 N.A. 0 0 0 6.6 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 53.3 86.6 46.6 N.A. 60 66.6 N.A. 6.6 20 20 26.6 N.A. 20 0 20 0
Percent
Protein Identity: N.A. N.A. N.A. 29.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 27 7 0 0 0 7 14 7 0 0 0 0 27 % A
% Cys: 7 0 0 0 7 7 0 0 0 7 0 0 7 0 0 % C
% Asp: 14 0 0 0 0 0 7 0 0 0 0 34 7 0 0 % D
% Glu: 20 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 14 0 7 27 27 7 7 7 20 34 20 0 0 % F
% Gly: 7 0 0 0 7 7 14 0 20 0 7 0 7 0 0 % G
% His: 0 0 7 7 20 0 0 0 14 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 0 14 7 % I
% Lys: 34 7 0 14 14 7 27 7 0 0 0 20 0 0 0 % K
% Leu: 0 0 0 0 0 0 14 0 7 14 20 0 7 0 0 % L
% Met: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 7 20 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 7 0 27 0 0 0 0 20 0 20 0 34 0 7 % P
% Gln: 7 27 7 0 7 14 7 34 0 0 0 7 0 7 0 % Q
% Arg: 7 0 0 0 7 14 0 0 0 0 7 7 0 34 0 % R
% Ser: 0 7 7 7 0 0 0 27 0 0 0 0 20 27 27 % S
% Thr: 0 0 7 7 0 7 0 0 14 20 0 0 0 0 20 % T
% Val: 0 0 0 34 7 0 7 14 7 40 0 0 0 14 7 % V
% Trp: 7 27 7 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 27 14 0 0 0 7 20 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _