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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT7 All Species: 30.61
Human Site: T582 Identified Species: 48.1
UniProt: Q9NVM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVM4 NP_061896.1 692 78459 T582 S E P W Q I L T F D F Q Q P V
Chimpanzee Pan troglodytes XP_511055 649 73905 D546 G F D V H I M D D M I K R A L
Rhesus Macaque Macaca mulatta XP_001099228 701 79288 A582 S E P R Q I L A F D F R Q L V
Dog Lupus familis XP_536808 691 78200 T582 S E P Q H I L T F D F R Q L V
Cat Felis silvestris
Mouse Mus musculus Q922X9 692 78283 T582 S K P Q E I L T F D F Q Q P I
Rat Rattus norvegicus Q5U4E8 693 78328 T582 S E P R Q I L T F D F Q Q P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505676 689 78245 T583 S E P Q E V M T F D F R Q P V
Chicken Gallus gallus Q5ZIB9 689 78053 L583 S N P Q E V L L F D F R K T V
Frog Xenopus laevis Q6PCI6 685 77273 T577 S E P I Q V M T F N F T E P V
Zebra Danio Brachydanio rerio A2AV36 683 76528 T577 T K P C P V M T F D F T Q C V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1V1 690 77927 S586 S E P Q E V L S V D F S N F G
Honey Bee Apis mellifera XP_392453 690 78204 K582 S L P F V I K K F D L T E N V
Nematode Worm Caenorhab. elegans Q9XW42 630 71248 I531 V K G D A V E I L R F P I D G
Sea Urchin Strong. purpuratus XP_780353 686 76862 T578 T Q Q F E L M T F D F S K A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944R7 724 80852 T617 F I W Q C G E T K I L S K E F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 93.5 87.5 N.A. 85.1 83.9 N.A. 74.8 68.3 64 62.2 N.A. 37.1 41 31 45.8
Protein Similarity: 100 92.6 96 93.5 N.A. 92.7 92.2 N.A. 84.8 82.3 77.8 76 N.A. 57.5 59.8 45.3 66.1
P-Site Identity: 100 6.6 73.3 73.3 N.A. 73.3 86.6 N.A. 66.6 46.6 60 46.6 N.A. 40 40 6.6 26.6
P-Site Similarity: 100 33.3 80 80 N.A. 93.3 93.3 N.A. 93.3 73.3 86.6 73.3 N.A. 60 53.3 20 80
Percent
Protein Identity: N.A. N.A. N.A. 29.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 7 0 0 0 0 0 14 0 % A
% Cys: 0 0 0 7 7 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 7 7 0 0 0 7 7 74 0 0 0 7 0 % D
% Glu: 0 47 0 0 34 0 14 0 0 0 0 0 14 7 0 % E
% Phe: 7 7 0 14 0 0 0 0 74 0 80 0 0 7 7 % F
% Gly: 7 0 7 0 0 7 0 0 0 0 0 0 0 0 14 % G
% His: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 0 47 0 7 0 7 7 0 7 0 20 % I
% Lys: 0 20 0 0 0 0 7 7 7 0 0 7 20 0 0 % K
% Leu: 0 7 0 0 0 7 47 7 7 0 14 0 0 14 7 % L
% Met: 0 0 0 0 0 0 34 0 0 7 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 7 0 0 7 7 0 % N
% Pro: 0 0 74 0 7 0 0 0 0 0 0 7 0 34 0 % P
% Gln: 0 7 7 40 27 0 0 0 0 0 0 20 47 0 0 % Q
% Arg: 0 0 0 14 0 0 0 0 0 7 0 27 7 0 0 % R
% Ser: 67 0 0 0 0 0 0 7 0 0 0 20 0 0 0 % S
% Thr: 14 0 0 0 0 0 0 60 0 0 0 20 0 7 0 % T
% Val: 7 0 0 7 7 40 0 0 7 0 0 0 0 0 54 % V
% Trp: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _