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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf11 All Species: 25.15
Human Site: S219 Identified Species: 50.3
UniProt: Q9NVM9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVM9 NP_060634.2 706 80225 S219 V G E D S L V S D R S K K E L
Chimpanzee Pan troglodytes XP_001144314 649 73350 E181 M L E D C V Q E T I H E H N K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852358 706 80174 S219 V G E D S L V S D R P K K E L
Cat Felis silvestris
Mouse Mus musculus Q8QZV7 732 82731 S219 V G E D S L V S D R P K K E L
Rat Rattus norvegicus NP_001103078 696 78898 S219 V G E D S L V S D R P K K E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514940 394 44854
Chicken Gallus gallus XP_416439 847 95735 S361 V G E D S L V S D R P K K E L
Frog Xenopus laevis Q6GLY5 715 80948 S219 V G E D S L V S D R P K K E L
Zebra Danio Brachydanio rerio NP_956177 704 79683 S219 Q G D D T L V S D R Q K K E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEX5 689 75709 I211 P S K K G L V I D H C H L V I
Honey Bee Apis mellifera XP_391996 674 75034 I204 V D Y C H L V I L N I F P N N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791410 695 76740 L218 L P I D H C E L C L V N I H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 N.A. 98.7 N.A. 92.3 93.9 N.A. 41.5 77.8 84.1 80 N.A. 37.1 46.8 N.A. 50.1
Protein Similarity: 100 91.9 N.A. 99.2 N.A. 94.5 96.1 N.A. 47.3 80.7 91.6 90 N.A. 57.3 65.5 N.A. 65
P-Site Identity: 100 13.3 N.A. 93.3 N.A. 93.3 93.3 N.A. 0 93.3 93.3 73.3 N.A. 20 20 N.A. 6.6
P-Site Similarity: 100 33.3 N.A. 93.3 N.A. 93.3 93.3 N.A. 0 93.3 93.3 86.6 N.A. 33.3 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 9 9 9 0 0 9 0 9 0 0 0 0 % C
% Asp: 0 9 9 75 0 0 0 0 67 0 0 0 0 0 0 % D
% Glu: 0 0 59 0 0 0 9 9 0 0 0 9 0 59 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 59 0 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 17 0 0 0 0 9 9 9 9 9 0 % H
% Ile: 0 0 9 0 0 0 0 17 0 9 9 0 9 0 9 % I
% Lys: 0 0 9 9 0 0 0 0 0 0 0 59 59 0 9 % K
% Leu: 9 9 0 0 0 75 0 9 9 9 0 0 9 0 59 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 9 0 17 9 % N
% Pro: 9 9 0 0 0 0 0 0 0 0 42 0 9 0 9 % P
% Gln: 9 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 % R
% Ser: 0 9 0 0 50 0 0 59 0 0 9 0 0 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % T
% Val: 59 0 0 0 0 9 75 0 0 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _