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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIC8B
All Species:
19.39
Human Site:
S374
Identified Species:
38.79
UniProt:
Q9NVN3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVN3
NP_060627
536
60840
S374
L
S
L
L
T
E
C
S
R
A
H
R
N
I
R
Chimpanzee
Pan troglodytes
XP_001162026
560
63476
S374
L
S
L
L
T
E
C
S
R
A
H
R
N
I
R
Rhesus Macaque
Macaca mulatta
XP_001083920
528
59373
R343
T
E
C
A
R
M
H
R
P
A
R
K
F
L
K
Dog
Lupus familis
XP_538415
566
64182
S374
L
S
L
L
T
E
C
S
R
A
H
R
N
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80XE1
560
63333
S374
L
S
L
L
T
E
C
S
R
A
H
R
N
I
R
Rat
Rattus norvegicus
Q80ZG0
520
58372
S374
L
S
L
L
T
E
C
S
R
A
H
R
N
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508465
507
56644
S368
E
K
R
I
D
K
G
S
C
Y
R
E
G
L
T
Chicken
Gallus gallus
Q5ZL77
539
61485
A350
L
N
L
L
T
E
S
A
R
V
H
R
Q
T
R
Frog
Xenopus laevis
Q45TX8
539
61255
L368
R
A
K
V
L
P
P
L
R
D
V
K
N
R
P
Zebra Danio
Brachydanio rerio
Q642H7
548
61977
A354
L
N
L
L
T
E
S
A
R
I
H
R
E
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W358
573
65583
A382
L
T
V
L
V
K
C
A
R
S
D
R
V
M
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GSX9
566
63429
C372
F
Q
V
L
A
R
L
C
T
D
S
K
Y
V
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
47
92
N.A.
91.7
87.5
N.A.
71.8
51.5
50.8
48.7
N.A.
30.8
N.A.
25.4
N.A.
Protein Similarity:
100
95
63.4
93.4
N.A.
93.9
91.9
N.A.
79.8
68.8
66.4
67.3
N.A.
50.4
N.A.
45.5
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
60
13.3
60
N.A.
40
N.A.
13.3
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
26.6
73.3
33.3
73.3
N.A.
80
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
0
25
0
50
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
50
9
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
17
9
0
0
0
0
% D
% Glu:
9
9
0
0
0
59
0
0
0
0
0
9
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
59
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
9
0
0
0
42
0
% I
% Lys:
0
9
9
0
0
17
0
0
0
0
0
25
0
0
9
% K
% Leu:
67
0
59
75
9
0
9
9
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
17
0
0
0
0
0
0
0
0
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
9
9
0
9
0
0
0
0
0
9
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
9
0
9
0
9
9
0
9
75
0
17
67
0
9
75
% R
% Ser:
0
42
0
0
0
0
17
50
0
9
9
0
0
0
0
% S
% Thr:
9
9
0
0
59
0
0
0
9
0
0
0
0
17
9
% T
% Val:
0
0
17
9
9
0
0
0
0
9
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _