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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIC8B All Species: 31.21
Human Site: S468 Identified Species: 62.42
UniProt: Q9NVN3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVN3 NP_060627 536 60840 S468 G R G D N W Y S E D E D T D T
Chimpanzee Pan troglodytes XP_001162026 560 63476 S468 G R G D N W Y S E D E D T D T
Rhesus Macaque Macaca mulatta XP_001083920 528 59373 S433 G R P E G Q Y S E D E D T D T
Dog Lupus familis XP_538415 566 64182 S474 G R G D N W Y S E D E D T D T
Cat Felis silvestris
Mouse Mus musculus Q80XE1 560 63333 S468 G R G D N W Y S E D E D T D T
Rat Rattus norvegicus Q80ZG0 520 58372 L452 Y G N A A G L L A A R G L L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508465 507 56644 L442 A A E F L F V L C K E R V D S
Chicken Gallus gallus Q5ZL77 539 61485 S444 G R E E G E Y S E D E D T D T
Frog Xenopus laevis Q45TX8 539 61255 S444 G R G E G C Y S E D D D T D T
Zebra Danio Brachydanio rerio Q642H7 548 61977 S448 G R D P G H Y S E D E D S D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W358 573 65583 S478 V E G T D Y S S D S E D S D T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9GSX9 566 63429 D468 N Q P K H A S D S E D S E T E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 47 92 N.A. 91.7 87.5 N.A. 71.8 51.5 50.8 48.7 N.A. 30.8 N.A. 25.4 N.A.
Protein Similarity: 100 95 63.4 93.4 N.A. 93.9 91.9 N.A. 79.8 68.8 66.4 67.3 N.A. 50.4 N.A. 45.5 N.A.
P-Site Identity: 100 100 73.3 100 N.A. 100 0 N.A. 13.3 73.3 73.3 66.6 N.A. 40 N.A. 0 N.A.
P-Site Similarity: 100 100 80 100 N.A. 100 0 N.A. 26.6 80 86.6 73.3 N.A. 66.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 9 9 0 0 9 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 9 34 9 0 0 9 9 67 17 75 0 84 0 % D
% Glu: 0 9 17 25 0 9 0 0 67 9 75 0 9 0 9 % E
% Phe: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 67 9 50 0 34 9 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 9 17 0 0 0 0 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 34 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 67 0 0 0 0 0 0 0 0 9 9 0 0 0 % R
% Ser: 0 0 0 0 0 0 17 75 9 9 0 9 17 0 9 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 0 59 9 75 % T
% Val: 9 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 9 67 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _