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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNL3L
All Species:
23.03
Human Site:
S271
Identified Species:
36.19
UniProt:
Q9NVN8
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVN8
NP_061940.1
582
65573
S271
G
K
S
S
L
I
N
S
L
K
R
S
R
A
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090251
581
65443
S270
G
K
S
S
L
I
N
S
L
K
R
S
R
A
C
Dog
Lupus familis
XP_538054
649
72418
S338
G
K
S
S
L
I
N
S
L
K
R
S
R
A
C
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGG6
577
65176
S265
G
K
S
S
L
I
N
S
L
K
R
S
R
A
C
Rat
Rattus norvegicus
Q811S9
538
60642
V222
F
K
I
K
K
K
V
V
P
F
Q
S
K
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510383
826
90308
N529
V
G
K
S
S
L
I
N
S
L
K
R
A
R
A
Chicken
Gallus gallus
XP_414249
686
76560
G289
E
Q
A
I
T
C
S
G
G
E
K
K
L
L
L
Frog
Xenopus laevis
Q7ZX41
542
60839
K235
P
G
G
Q
V
L
L
K
I
L
H
S
L
C
P
Zebra Danio
Brachydanio rerio
Q6DRP2
561
62883
H233
G
T
N
A
V
L
D
H
S
R
A
A
S
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT06
581
65966
S253
I
G
A
E
L
L
M
S
M
L
G
N
Y
C
R
Honey Bee
Apis mellifera
XP_001119916
573
65075
N257
N
Y
C
R
N
V
G
N
V
K
T
S
I
R
V
Nematode Worm
Caenorhab. elegans
Q21086
556
62320
E216
A
F
K
A
S
T
Q
E
Q
K
S
N
I
G
R
Sea Urchin
Strong. purpuratus
XP_783153
454
50984
P157
E
V
L
D
A
R
D
P
I
G
S
R
C
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142481
594
66162
S284
G
K
S
S
L
I
N
S
L
K
R
S
R
V
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187361
582
65767
S272
G
K
S
S
L
I
N
S
L
K
R
A
H
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
80.2
N.A.
87.1
32.6
N.A.
38.8
30.3
31.2
30.9
N.A.
36.4
39.1
37.9
36.9
Protein Similarity:
100
N.A.
97.5
84.7
N.A.
92.9
52.9
N.A.
49.8
49.1
50.5
51
N.A.
53.7
58.4
56.8
51
P-Site Identity:
100
N.A.
100
100
N.A.
100
20
N.A.
6.6
0
6.6
6.6
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
33.3
N.A.
26.6
33.3
26.6
53.3
N.A.
40
33.3
20
13.3
Percent
Protein Identity:
N.A.
35
N.A.
34
N.A.
N.A.
Protein Similarity:
N.A.
52.5
N.A.
51.5
N.A.
N.A.
P-Site Identity:
N.A.
86.6
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
14
7
0
0
0
0
0
7
14
7
27
14
% A
% Cys:
0
0
7
0
0
7
0
0
0
0
0
0
7
20
34
% C
% Asp:
0
0
0
7
0
0
14
0
0
0
0
0
0
0
0
% D
% Glu:
14
0
0
7
0
0
0
7
0
7
0
0
0
0
0
% E
% Phe:
7
7
0
0
0
0
0
0
0
7
0
0
0
0
7
% F
% Gly:
47
20
7
0
0
0
7
7
7
7
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
7
0
7
0
0
% H
% Ile:
7
0
7
7
0
40
7
0
14
0
0
0
14
7
0
% I
% Lys:
0
47
14
7
7
7
0
7
0
54
14
7
7
0
0
% K
% Leu:
0
0
7
0
47
27
7
0
40
20
0
0
14
14
7
% L
% Met:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
7
0
40
14
0
0
0
14
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
7
7
0
0
0
0
0
7
% P
% Gln:
0
7
0
7
0
0
7
0
7
0
7
0
0
0
0
% Q
% Arg:
0
0
0
7
0
7
0
0
0
7
40
14
34
14
14
% R
% Ser:
0
0
40
47
14
0
7
47
14
0
14
54
7
0
0
% S
% Thr:
0
7
0
0
7
7
0
0
0
0
7
0
0
0
0
% T
% Val:
7
7
0
0
14
7
7
7
7
0
0
0
0
14
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _