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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNL3L All Species: 12.42
Human Site: S38 Identified Species: 19.52
UniProt: Q9NVN8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVN8 NP_061940.1 582 65573 S38 Q N G K K A T S K V P S A P H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090251 581 65443 S37 Q N G K K A T S K V P S V P H
Dog Lupus familis XP_538054 649 72418 S105 Q N G K K A A S K V A S A P Q
Cat Felis silvestris
Mouse Mus musculus Q6PGG6 577 65176 S31 Q N G K K V T S R P S S A P Q
Rat Rattus norvegicus Q811S9 538 60642 K45 K R G H K K P K K D P G V P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510383 826 90308 R32 R S L R C P A R E P R A A G Y
Chicken Gallus gallus XP_414249 686 76560 T64 V Q R T G S F T G K A T A F T
Frog Xenopus laevis Q7ZX41 542 60839 K45 K S G P R K H K K D I T V P N
Zebra Danio Brachydanio rerio Q6DRP2 561 62883 A45 K Q G I S R K A K K D I G V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT06 581 65966 K46 K N P K K G S K K Q K L I Q I
Honey Bee Apis mellifera XP_001119916 573 65075 K45 K H P K N K P K I I E V P N Q
Nematode Worm Caenorhab. elegans Q21086 556 62320 I49 T N K K E K T I S V P N S C P
Sea Urchin Strong. purpuratus XP_783153 454 50984 R8 M P T K G Q P R K M K S K R M
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001142481 594 66162 E49 A G Q R R K V E K D P G I P N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187361 582 65767 P45 K L G L H R K P R V E K D P G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.2 80.2 N.A. 87.1 32.6 N.A. 38.8 30.3 31.2 30.9 N.A. 36.4 39.1 37.9 36.9
Protein Similarity: 100 N.A. 97.5 84.7 N.A. 92.9 52.9 N.A. 49.8 49.1 50.5 51 N.A. 53.7 58.4 56.8 51
P-Site Identity: 100 N.A. 93.3 80 N.A. 66.6 33.3 N.A. 6.6 6.6 20 13.3 N.A. 26.6 6.6 33.3 20
P-Site Similarity: 100 N.A. 93.3 80 N.A. 73.3 46.6 N.A. 46.6 26.6 53.3 26.6 N.A. 40 26.6 53.3 26.6
Percent
Protein Identity: N.A. 35 N.A. 34 N.A. N.A.
Protein Similarity: N.A. 52.5 N.A. 51.5 N.A. N.A.
P-Site Identity: N.A. 20 N.A. 20 N.A. N.A.
P-Site Similarity: N.A. 40 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 20 14 7 0 0 14 7 34 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 20 7 0 7 0 0 % D
% Glu: 0 0 0 0 7 0 0 7 7 0 14 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % F
% Gly: 0 7 54 0 14 7 0 0 7 0 0 14 7 7 7 % G
% His: 0 7 0 7 7 0 7 0 0 0 0 0 0 0 14 % H
% Ile: 0 0 0 7 0 0 0 7 7 7 7 7 14 0 7 % I
% Lys: 40 0 7 54 40 34 14 27 60 14 14 7 7 0 0 % K
% Leu: 0 7 7 7 0 0 0 0 0 0 0 7 0 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % M
% Asn: 0 40 0 0 7 0 0 0 0 0 0 7 0 7 20 % N
% Pro: 0 7 14 7 0 7 20 7 0 14 34 0 7 54 14 % P
% Gln: 27 14 7 0 0 7 0 0 0 7 0 0 0 7 20 % Q
% Arg: 7 7 7 14 14 14 0 14 14 0 7 0 0 7 0 % R
% Ser: 0 14 0 0 7 7 7 27 7 0 7 34 7 0 0 % S
% Thr: 7 0 7 7 0 0 27 7 0 0 0 14 0 0 7 % T
% Val: 7 0 0 0 0 7 7 0 0 34 0 7 20 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _