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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNL3L
All Species:
14.24
Human Site:
S380
Identified Species:
22.38
UniProt:
Q9NVN8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVN8
NP_061940.1
582
65573
S380
K
K
K
G
G
L
Y
S
Q
E
Q
A
A
K
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090251
581
65443
S379
K
K
K
G
G
L
Y
S
Q
E
Q
A
A
K
A
Dog
Lupus familis
XP_538054
649
72418
S447
K
K
K
G
G
V
Y
S
H
E
Q
A
A
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGG6
577
65176
S374
K
K
K
G
G
V
Y
S
Q
E
Q
A
A
K
A
Rat
Rattus norvegicus
Q811S9
538
60642
R327
P
A
S
I
E
V
L
R
P
L
E
A
A
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510383
826
90308
L633
L
A
R
R
L
G
K
L
K
K
G
G
T
P
D
Chicken
Gallus gallus
XP_414249
686
76560
R415
T
K
S
M
Q
A
V
R
I
D
K
Q
M
K
I
Frog
Xenopus laevis
Q7ZX41
542
60839
L343
C
S
K
Q
E
L
M
L
H
Y
T
I
A
D
Y
Zebra Danio
Brachydanio rerio
Q6DRP2
561
62883
P341
V
E
E
K
E
E
S
P
Q
E
A
V
R
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT06
581
65966
C364
R
A
S
K
E
Y
F
C
T
M
Y
D
I
T
N
Honey Bee
Apis mellifera
XP_001119916
573
65075
M363
S
K
P
Q
I
M
E
M
Y
N
I
T
E
Y
S
Nematode Worm
Caenorhab. elegans
Q21086
556
62320
K354
A
I
L
R
R
C
S
K
E
T
I
M
L
H
Y
Sea Urchin
Strong. purpuratus
XP_783153
454
50984
T261
C
R
N
V
D
I
K
T
S
I
T
V
G
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142481
594
66162
D395
L
K
K
G
G
V
V
D
V
E
A
A
A
R
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187361
582
65767
D383
L
K
K
G
G
L
V
D
I
D
A
A
A
R
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
80.2
N.A.
87.1
32.6
N.A.
38.8
30.3
31.2
30.9
N.A.
36.4
39.1
37.9
36.9
Protein Similarity:
100
N.A.
97.5
84.7
N.A.
92.9
52.9
N.A.
49.8
49.1
50.5
51
N.A.
53.7
58.4
56.8
51
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
20
N.A.
0
13.3
20
13.3
N.A.
0
6.6
0
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
33.3
N.A.
20
26.6
20
26.6
N.A.
13.3
20
6.6
20
Percent
Protein Identity:
N.A.
35
N.A.
34
N.A.
N.A.
Protein Similarity:
N.A.
52.5
N.A.
51.5
N.A.
N.A.
P-Site Identity:
N.A.
46.6
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
0
0
0
7
0
0
0
0
20
47
54
0
34
% A
% Cys:
14
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
14
0
14
0
7
0
7
7
% D
% Glu:
0
7
7
0
27
7
7
0
7
40
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
40
40
7
0
0
0
0
7
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
0
0
7
0
% H
% Ile:
0
7
0
7
7
7
0
0
14
7
14
7
7
7
20
% I
% Lys:
27
54
47
14
0
0
14
7
7
7
7
0
0
34
0
% K
% Leu:
20
0
7
0
7
27
7
14
0
7
0
0
7
0
7
% L
% Met:
0
0
0
7
0
7
7
7
0
7
0
7
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
0
0
0
7
7
% N
% Pro:
7
0
7
0
0
0
0
7
7
0
0
0
0
7
0
% P
% Gln:
0
0
0
14
7
0
0
0
27
0
27
7
0
0
0
% Q
% Arg:
7
7
7
14
7
0
0
14
0
0
0
0
7
14
0
% R
% Ser:
7
7
20
0
0
0
14
27
7
0
0
0
0
7
7
% S
% Thr:
7
0
0
0
0
0
0
7
7
7
14
7
7
7
0
% T
% Val:
7
0
0
7
0
27
20
0
7
0
0
14
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
27
0
7
7
7
0
0
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _