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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNL3L
All Species:
18.79
Human Site:
Y351
Identified Species:
29.52
UniProt:
Q9NVN8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVN8
NP_061940.1
582
65573
Y351
L
E
E
I
S
N
Y
Y
G
V
S
G
F
Q
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090251
581
65443
Y350
L
E
E
I
S
N
Y
Y
G
V
S
G
F
Q
T
Dog
Lupus familis
XP_538054
649
72418
Y418
L
E
E
I
S
N
Y
Y
G
I
S
G
F
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGG6
577
65176
Y345
L
E
E
I
S
S
Y
Y
G
V
S
G
F
Q
T
Rat
Rattus norvegicus
Q811S9
538
60642
I298
P
L
D
K
Q
I
T
I
I
D
S
P
C
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510383
826
90308
K604
A
I
L
R
R
C
N
K
E
Q
I
I
Q
H
Y
Chicken
Gallus gallus
XP_414249
686
76560
K386
V
G
F
P
N
V
G
K
S
S
I
I
N
S
I
Frog
Xenopus laevis
Q7ZX41
542
60839
M314
H
N
P
P
V
A
L
M
L
R
S
A
S
E
S
Zebra Danio
Brachydanio rerio
Q6DRP2
561
62883
D312
T
K
K
V
K
M
I
D
S
P
G
I
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT06
581
65966
L335
G
E
N
S
H
A
V
L
K
N
A
Q
R
V
G
Honey Bee
Apis mellifera
XP_001119916
573
65075
N334
E
S
S
V
A
L
K
N
A
V
K
I
Q
S
L
Nematode Worm
Caenorhab. elegans
Q21086
556
62320
I325
S
Q
K
D
L
D
P
I
E
V
A
L
K
N
A
Sea Urchin
Strong. purpuratus
XP_783153
454
50984
S232
V
P
V
S
M
S
S
S
E
L
L
Q
T
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142481
594
66162
Y366
H
E
K
L
L
S
L
Y
K
V
P
N
F
G
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187361
582
65767
Y354
K
D
M
L
V
T
L
Y
K
I
P
S
F
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
80.2
N.A.
87.1
32.6
N.A.
38.8
30.3
31.2
30.9
N.A.
36.4
39.1
37.9
36.9
Protein Similarity:
100
N.A.
97.5
84.7
N.A.
92.9
52.9
N.A.
49.8
49.1
50.5
51
N.A.
53.7
58.4
56.8
51
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
6.6
N.A.
0
0
6.6
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
0
13.3
20
20
N.A.
13.3
20
33.3
20
Percent
Protein Identity:
N.A.
35
N.A.
34
N.A.
N.A.
Protein Similarity:
N.A.
52.5
N.A.
51.5
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
14
0
0
7
0
14
7
0
7
20
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
7
7
7
0
7
0
7
0
7
0
0
0
0
0
% D
% Glu:
7
40
27
0
0
0
0
0
20
0
0
0
0
14
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
40
7
0
% F
% Gly:
7
7
0
0
0
0
7
0
27
0
7
27
0
7
7
% G
% His:
14
0
0
0
7
0
0
0
0
0
0
0
0
7
7
% H
% Ile:
0
7
0
27
0
7
7
14
7
14
14
27
0
0
14
% I
% Lys:
7
7
20
7
7
0
7
14
20
0
7
0
7
0
0
% K
% Leu:
27
7
7
14
14
7
20
7
7
7
7
7
7
0
7
% L
% Met:
0
0
7
0
7
7
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
7
20
7
7
0
7
0
7
7
7
0
% N
% Pro:
7
7
7
14
0
0
7
0
0
7
14
7
0
0
0
% P
% Gln:
0
7
0
0
7
0
0
0
0
7
0
14
14
27
0
% Q
% Arg:
0
0
0
7
7
0
0
0
0
7
0
0
7
0
0
% R
% Ser:
7
7
7
14
27
20
7
7
14
7
40
7
7
20
14
% S
% Thr:
7
0
0
0
0
7
7
0
0
0
0
0
7
0
27
% T
% Val:
14
0
7
14
14
7
7
0
0
40
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
27
40
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _