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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX18
All Species:
12.12
Human Site:
S105
Identified Species:
20.51
UniProt:
Q9NVP1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVP1
NP_006764.3
670
75407
S105
A
A
M
Q
S
S
N
S
E
S
K
K
K
K
K
Chimpanzee
Pan troglodytes
XP_515753
670
75474
S105
A
A
M
Q
S
S
N
S
E
S
K
K
K
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533327
669
75188
S105
A
E
T
Q
P
P
N
S
E
S
K
K
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K363
660
74162
T92
K
S
P
Q
K
L
T
T
L
A
N
G
E
A
A
Rat
Rattus norvegicus
NP_001006997
674
75530
D105
A
A
A
M
P
S
T
D
P
E
L
K
K
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422125
662
73819
P98
G
E
Q
A
A
P
G
P
E
A
V
G
A
K
R
Frog
Xenopus laevis
NP_001084744
638
72228
A94
N
V
A
K
A
E
G
A
D
A
K
K
A
K
Q
Zebra Danio
Brachydanio rerio
NP_001003411
653
73486
S92
A
T
G
E
S
T
T
S
S
V
K
K
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VD51
680
76909
D100
S
D
S
E
S
D
D
D
E
Q
E
D
E
A
D
Honey Bee
Apis mellifera
XP_397167
429
49197
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783274
680
77265
K101
S
D
D
Q
S
P
D
K
K
V
P
R
T
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LIH9
568
63798
V52
Q
K
K
S
E
K
K
V
K
K
V
R
G
K
I
Baker's Yeast
Sacchar. cerevisiae
Q03532
505
56699
Red Bread Mold
Neurospora crassa
Q7S2N9
578
64641
Q62
D
A
Q
K
A
E
E
Q
Q
D
G
D
E
V
I
Conservation
Percent
Protein Identity:
100
98.3
N.A.
89.6
N.A.
86.4
85.1
N.A.
N.A.
73.5
73.7
71.9
N.A.
59.7
47.6
N.A.
55.8
Protein Similarity:
100
99
N.A.
95
N.A.
90.7
90.5
N.A.
N.A.
82.2
84.6
82.6
N.A.
73.8
55.3
N.A.
70.2
P-Site Identity:
100
100
N.A.
73.3
N.A.
6.6
46.6
N.A.
N.A.
13.3
20
46.6
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
73.3
N.A.
33.3
46.6
N.A.
N.A.
33.3
60
60
N.A.
46.6
0
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.6
48.6
50.9
Protein Similarity:
N.A.
N.A.
N.A.
64.1
64
69.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
29
15
8
22
0
0
8
0
22
0
0
22
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
8
0
0
8
15
15
8
8
0
15
0
0
8
% D
% Glu:
0
15
0
15
8
15
8
0
36
8
8
0
22
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
15
0
0
0
8
15
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
8
8
8
15
8
8
8
8
15
8
36
43
29
58
36
% K
% Leu:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% L
% Met:
0
0
15
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
22
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
15
22
0
8
8
0
8
0
0
0
0
% P
% Gln:
8
0
15
36
0
0
0
8
8
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
8
% R
% Ser:
15
8
8
8
36
22
0
29
8
22
0
0
0
0
0
% S
% Thr:
0
8
8
0
0
8
22
8
0
0
0
0
8
0
0
% T
% Val:
0
8
0
0
0
0
0
8
0
15
15
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _