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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX18
All Species:
6.06
Human Site:
S136
Identified Species:
10.26
UniProt:
Q9NVP1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVP1
NP_006764.3
670
75407
S136
K
T
E
N
K
G
K
S
E
E
E
S
A
E
T
Chimpanzee
Pan troglodytes
XP_515753
670
75474
S136
K
T
E
N
K
G
K
S
E
E
E
S
A
E
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533327
669
75188
D135
S
K
T
E
D
K
G
D
S
E
E
G
T
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K363
660
74162
T126
A
N
D
A
G
P
D
T
K
K
A
K
T
E
E
Rat
Rattus norvegicus
NP_001006997
674
75530
E140
E
G
T
E
A
R
E
E
P
E
G
A
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422125
662
73819
A128
T
E
T
K
K
A
K
A
E
E
D
V
S
V
E
Frog
Xenopus laevis
NP_001084744
638
72228
D124
N
H
V
E
K
K
E
D
E
E
E
N
G
P
T
Zebra Danio
Brachydanio rerio
NP_001003411
653
73486
E121
Q
Q
E
E
G
N
L
E
T
V
K
C
P
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VD51
680
76909
A144
D
E
E
E
P
V
P
A
K
K
T
K
L
L
P
Honey Bee
Apis mellifera
XP_397167
429
49197
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783274
680
77265
A155
D
S
S
F
A
S
L
A
D
R
V
S
E
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LIH9
568
63798
I80
E
D
E
K
N
I
V
I
V
G
K
G
I
M
T
Baker's Yeast
Sacchar. cerevisiae
Q03532
505
56699
E17
R
D
S
E
S
T
E
E
P
V
V
D
E
K
S
Red Bread Mold
Neurospora crassa
Q7S2N9
578
64641
L90
D
A
E
A
G
D
E
L
T
K
T
N
D
S
L
Conservation
Percent
Protein Identity:
100
98.3
N.A.
89.6
N.A.
86.4
85.1
N.A.
N.A.
73.5
73.7
71.9
N.A.
59.7
47.6
N.A.
55.8
Protein Similarity:
100
99
N.A.
95
N.A.
90.7
90.5
N.A.
N.A.
82.2
84.6
82.6
N.A.
73.8
55.3
N.A.
70.2
P-Site Identity:
100
100
N.A.
13.3
N.A.
6.6
13.3
N.A.
N.A.
26.6
33.3
13.3
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
20
N.A.
33.3
33.3
N.A.
N.A.
46.6
46.6
26.6
N.A.
26.6
0
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.6
48.6
50.9
Protein Similarity:
N.A.
N.A.
N.A.
64.1
64
69.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
15
15
8
0
22
0
0
8
8
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
22
15
8
0
8
8
8
15
8
0
8
8
8
0
0
% D
% Glu:
15
15
43
43
0
0
29
22
29
43
29
0
15
36
22
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
22
15
8
0
0
8
8
15
15
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% I
% Lys:
15
8
0
15
29
15
22
0
15
22
15
15
0
8
0
% K
% Leu:
0
0
0
0
0
0
15
8
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
8
0
15
8
8
0
0
0
0
0
15
0
0
8
% N
% Pro:
0
0
0
0
8
8
8
0
15
0
0
0
8
8
8
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
0
0
0
15
0
% Q
% Arg:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
8
15
0
8
8
0
15
8
0
0
22
8
8
8
% S
% Thr:
8
15
22
0
0
8
0
8
15
0
15
0
15
0
36
% T
% Val:
0
0
8
0
0
8
8
0
8
15
15
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _